SCHEMBL14918287

SCHEMBL14918287

[N-]=[N+]=NCCC(=O)Nc1ccc(O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A1 P04798 2/20 0.57
▸ TRPV1 Q8NER1 3/20 0.49
▸ GAA P10253 2/20 0.48
▸ PSMB11 A5LHX3 2/20 0.44
▸ PSMA7 O14818 2/20 0.44
▸ PSMB1 P20618 2/20 0.44
▸ PSMA1 P25786 2/20 0.44
▸ PSMA2 P25787 2/20 0.44
▸ PSMA3 P25788 2/20 0.44
▸ PSMA4 P25789 2/20 0.44
▸ PSMB8 P28062 2/20 0.44
▸ PSMB9 P28065 2/20 0.44
▸ PSMA5 P28066 2/20 0.44
▸ PSMB4 P28070 2/20 0.44
▸ PSMB6 P28072 2/20 0.44
▸ PSMB5 P28074 2/20 0.44
▸ PSMB10 P40306 2/20 0.44
▸ PSMB3 P49720 2/20 0.44
▸ PSMB2 P49721 2/20 0.44
▸ PSMA6 P60900 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16311230 0.84 CYP1A2 (0.50) CYP1A1GAAPOLBALDH1A1MAPT
SCHEMBL14918751 0.82 POLB (0.39) CYP1A1HDAC4POLBMEN1CYP3A4
SCHEMBL27937384 0.80 CYP1A1 (0.84) CYP1A1TRPV1GAAPSMB11PSMA7
SCHEMBL13804328 0.79 CNR2 (0.66) CYP1A1TRPV1GAAPSMB11PSMA7
SCHEMBL18897622 0.74 HDAC4 (0.59) HDAC4CYP3A4CYP1A2BRD4NR1I2
SCHEMBL31203439 0.73 HDAC4 (0.62) HDAC4CYP3A4BRD4NR1I2HDAC3
SCHEMBL31203346 0.73 HDAC4 (0.62) HDAC4CYP3A4BRD4NR1I2HDAC3
SCHEMBL31203361 0.73 HDAC4 (0.62) HDAC4CYP3A4BRD4NR1I2HDAC3
SCHEMBL19150356 0.73 CYP1A1 (0.67) CYP1A1TRPV1GAAPSMB11PSMA7
SCHEMBL2205077 0.73 CYP1A1 (0.67) CYP1A1TRPV1GAAPSMB11PSMA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11944618-B2 Subcutaneous delivery of polymer conjugates of therapeutic agents SERINA THERAPEUTICS, INC. (US) 2024-04-02 — — US disclosed
US-20220354841-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS SERINA THERAPEUTICS, INC. (US) 2022-11-10 — — US disclosed
US-11298350-B2 Subcutaneous delivery of polymer conjugates of therapeutics agents SERINA THERAPEUTICS, INC. (US) 2022-04-12 — — US disclosed
US-20200093816-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTICS AGENTS SERINA THERAPEUTICS (AL), INC. 2020-03-26 — — US disclosed
US-20200093816-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTICS AGENTS SERINA THERAPEUTICS (AL), INC. 2020-03-26 — — US disclosed
EP-2773379-B1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS SERINA THERAPEUTICS INC (US) 2019-10-09 — — EP disclosed
EP-2773379-B1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS SERINA THERAPEUTICS INC (US) 2019-10-09 — — EP disclosed
US-10426768-B2 Subcutaneous delivery of polymer conjugates of therapeutic agents Sarina Therapeutics, Inc. (US) 2019-10-01 — — US disclosed
US-10426768-B2 Subcutaneous delivery of polymer conjugates of therapeutic agents Sarina Therapeutics, Inc. (US) 2019-10-01 — — US disclosed
US-20170202972-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS SERINA THERAPEUTICS (AL), INC. 2017-07-20 — — US disclosed
US-20170202972-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS SERINA THERAPEUTICS (AL), INC. 2017-07-20 — — US disclosed
US-20170202972-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS SERINA THERAPEUTICS (AL), INC. 2017-07-20 — — US disclosed
US-20140271527-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS SERINA THERAPEUTICS, INC. (US) 2014-09-18 — — US disclosed
US-20140271527-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS SERINA THERAPEUTICS, INC. (US) 2014-09-18 — — US disclosed
US-20140271527-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS SERINA THERAPEUTICS, INC. (US) 2014-09-18 — — US disclosed
EP-2773379-A2 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS Serina Therapeutics, Inc. (US) 2014-09-10 — — EP disclosed
WO-2013067199-A2 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS SERINA THERAPEUTICS, INC. (US) 2013-05-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10426768-B2 Subcutaneous delivery of polymer conjugates of therapeutic agents CD44, CD47, LNPEP CYP1A1 4638/4885TRPV1 4845/4885GAA 229/4885
US-11944618-B2 Subcutaneous delivery of polymer conjugates of therapeutic agents CD44, CD47, LNPEP CYP1A1 4670/4885TRPV1 4847/4885GAA 283/4885
US-20170202972-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS CD44, CD47, LNPEP CYP1A1 4638/4885TRPV1 4845/4885GAA 229/4885
US-20200093816-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTICS AGENTS CD44, CD47, LNPEP CYP1A1 4469/4885TRPV1 4824/4885GAA 108/4885
US-20140271527-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS CD44, CD47, LNPEP CYP1A1 4638/4885TRPV1 4845/4885GAA 229/4885
US-11298350-B2 Subcutaneous delivery of polymer conjugates of therapeutics agents CD44, CD47, LNPEP CYP1A1 4469/4885TRPV1 4824/4885GAA 108/4885
US-20220354841-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS CD44, CD47, LNPEP CYP1A1 4638/4885TRPV1 4845/4885GAA 229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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