Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918287 | 0.84 | CYP1A1 (0.57) | CYP1A2CYP2C9POLBCA12CA2 | |
| SCHEMBL14918751 | 0.79 | POLB (0.39) | CYP1A2POLBCYP1A1MAPT | |
| SCHEMBL7824720 | 0.76 | CYP1A1 (0.70) | CYP1A2CYP2C9POLBCA12CA2 | |
| SCHEMBL11031322 | 0.76 | CYP1A2 (0.67) | CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL18897622 | 0.75 | HDAC4 (0.59) | CYP1A2 | |
| SCHEMBL4683731 | 0.75 | CYP1A2 (0.56) | CYP1A2CYP2C9POLBCA12CA2 | |
| SCHEMBL265614 | 0.75 | TP53 (0.70) | CYP1A2CYP2C9POLBCA12CA2 | |
| SCHEMBL11520695 | 0.75 | CA2 (0.58) | CYP1A2CYP2C9POLBCA12CA2 | |
| SCHEMBL28010779 | 0.75 | POLB (0.57) | CYP1A2CYP2C9POLBCA12CA2 | |
| SCHEMBL5192063 | 0.75 | POLB (0.57) | CYP1A2CYP2C9POLBCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9108943-B2 | Photoreactive benzamide probes for histone deacetylase 2 | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-08-18 | — | — | US | disclosed |
| US-9108943-B2 | Photoreactive benzamide probes for histone deacetylase 2 | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-08-18 | — | — | US | disclosed |
| US-20140371469-A1 | PHOTOREACTIVE BENZAMIDE PROBES FOR HISTONE DEACETYLASE 2 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-12-18 | — | — | US | disclosed |
| US-20140371469-A1 | PHOTOREACTIVE BENZAMIDE PROBES FOR HISTONE DEACETYLASE 2 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371469-A1 | PHOTOREACTIVE BENZAMIDE PROBES FOR HISTONE DEACETYLASE 2 | HDAC1, BRDT, HDAC2 | CYP1A2 2445/4885CYP2C9 3867/4885POLB 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.