Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918287 | 0.82 | CYP1A1 (0.57) | POLBHDAC8TP53HDAC3HDAC1 | |
| SCHEMBL16311230 | 0.79 | CYP1A2 (0.50) | POLBMAPTCYP1A1CYP1A2 | |
| SCHEMBL7649864 | 0.75 | TP53 (0.44) | POLBHDAC8TP53HDAC3HDAC1 | |
| SCHEMBL7654899 | 0.74 | TP53 (0.43) | POLBHDAC8TP53HDAC3HDAC1 | |
| SCHEMBL1353608 | 0.74 | TP53 (0.43) | POLBHDAC8TP53HDAC3HDAC1 | |
| SCHEMBL145468 | 0.74 | TP53 (0.67) | HDAC8TP53HDAC3HDAC1HDAC2 | |
| SCHEMBL3337034 | 0.74 | CYP1A1 (0.65) | POLBTP53L3MBTL1MAPTCYP1A1 | |
| SCHEMBL7648450 | 0.74 | TP53 (0.47) | POLBTP53HDAC1HDAC2HDAC6 | |
| SCHEMBL2181711 | 0.74 | TERT (0.51) | HDAC8TP53HDAC3HDAC1HDAC2 | |
| SCHEMBL7648767 | 0.73 | MEN1 (0.45) | POLBHDAC8TP53HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773379-A2 | SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS | Serina Therapeutics, Inc. (US) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013067199-A2 | SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS | SERINA THERAPEUTICS, INC. (US) | 2013-05-10 | — | — | WO | disclosed |