Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632209 | 0.82 | NPSR1 (0.50) | NPSR1KDM4EHPGDHTTRECQL | |
| SCHEMBL21579552 | 0.80 | NPSR1 (0.48) | NPSR1KDM4EHPGDHTTRECQL | |
| SCHEMBL10797763 | 0.80 | MEN1 (0.56) | NPSR1KDM4EHPGDHTTRECQL | |
| SCHEMBL28384135 | 0.76 | KDM4E (0.50) | NPSR1KDM4EHPGDHTTRECQL | |
| SCHEMBL28253909 | 0.76 | KDM4E (0.50) | NPSR1KDM4EHPGDHTTRECQL | |
| SCHEMBL8081387 | 0.76 | CA9 (0.52) | NPSR1KDM4EHPGDHTTRECQL | |
| SCHEMBL9439409 | 0.76 | KDM4E (0.50) | NPSR1KDM4EHPGDHTTRECQL | |
| SCHEMBL239971 | 0.76 | KDM4E (0.50) | NPSR1KDM4EHPGDHTTRECQL | |
| SCHEMBL195068 | 0.76 | CA9 (0.52) | NPSR1KDM4EHPGDHTTRECQL | |
| SCHEMBL6832573 | 0.76 | KDM4E (0.50) | NPSR1KDM4EHPGDHTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624185-A | LRRK2 inhibitor compound, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-03-01 | — | — | CN | claimed |
| CN-117624185-A | LRRK2 inhibitor compound, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-115667226-A | Tricyclic compounds as EGFR inhibitors | 齐鲁制药有限公司 | 2023-01-31 | — | — | CN | disclosed |
| EP-3037426-B1 | PHOSPHORUS-CONTAINING COMPOUND, AND CURABLE EPOXY RESIN COMPOSITION CONTAINING SAME | ADEKA CORP (JP) | 2021-06-23 | — | — | EP | disclosed |
| US-10562924-B2 | Phosphorus-containing compound, and curable epoxy resin composition containing same | ADEKA CORPORATION (JP) | 2020-02-18 | — | — | US | disclosed |
| US-20160152643-A1 | PHOSPHORUS-CONTAINING COMPOUND, AND CURABLE EPOXY RESIN COMPOSITION CONTAINING SAME | ADEKA CORPORATION (JP) | 2016-06-02 | — | — | US | disclosed |
| US-20160152643-A1 | PHOSPHORUS-CONTAINING COMPOUND, AND CURABLE EPOXY RESIN COMPOSITION CONTAINING SAME | ADEKA CORPORATION (JP) | 2016-06-02 | — | — | US | disclosed |
| EP-2300013-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | ARIAD Pharmaceuticals, Inc (US) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009143389-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | ARIAD PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562924-B2 | Phosphorus-containing compound, and curable epoxy resin composition containing same | EPB41, GRIA4, PTGER4 | NPSR1 793/4885KDM4E 614/4885HPGD 3106/4885 |
| US-20160152643-A1 | PHOSPHORUS-CONTAINING COMPOUND, AND CURABLE EPOXY RESIN COMPOSITION CONTAINING SAME | EPB41, GRIA4, PTGER4 | NPSR1 793/4885KDM4E 614/4885HPGD 3106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.