SCHEMBL21579552

SCHEMBL21579552

CP(=O)(Nc1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.48
KDM4E B2RXH2 1/20 0.45
HPGD P15428 2/20 0.44
HTT P42858 2/20 0.44
ESR1 P03372 1/20 0.43
LMNA P02545 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
PKM P14618 1/20 0.42
RECQL P46063 1/20 0.41
CA2 P00918 2/20 0.41
CA4 P22748 2/20 0.41
CA5A P35218 2/20 0.41
ALDH1A1 P00352 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
ALOX12 P18054 1/20 0.40
PTGS1 P23219 1/20 0.40
SLC6A2 P23975 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1491874 0.80 NPSR1 (0.56) NPSR1KDM4EHPGDHTTLMNA
SCHEMBL28661605 0.78 PKM (0.45) NPSR1KDM4EHPGDHTTMEN1
SCHEMBL31252468 0.78 L3MBTL1 (0.49) MEN1KMT2APKMTDP1L3MBTL1
SCHEMBL13043277 0.76 KDM4E (0.48) NPSR1KDM4EHPGDHTTLMNA
SCHEMBL16868500 0.76 KCNA5 (0.59) NPSR1KDM4EHPGDHTTLMNA
SCHEMBL8632209 0.74 NPSR1 (0.50) NPSR1KDM4EHPGDHTTESR1
SCHEMBL5169942 0.74 KDM4E (0.47) NPSR1KDM4EHPGDHTTLMNA
SCHEMBL7533388 0.74 KCNA5 (0.58) NPSR1KDM4EHPGDHTTESR1
Hydrochloric Acid SCHEMBL28020743 0.74 KCNA5 (0.58) NPSR1KDM4EHPGDHTTLMNA
SCHEMBL5169946 0.73 CA2 (0.52) NPSR1KDM4EHTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230235116-A1 HIGH-TEMPERATURE SELF-CROSSLINKING-BASED FLAME-RETARDANT ANTI-DRIPPING COPOLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SICHUAN UNIVERSITY (CN) 2023-07-27 US disclosed
US-20190352318-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-11-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190352318-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM NPSR1 2151/4885KDM4E 3088/4885HPGD 1381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.