SCHEMBL8081387

SCHEMBL8081387

O=P(O)(Nc1ccccc1)Nc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
KDM4E B2RXH2 1/20 0.50
NPSR1 Q6W5P4 1/20 0.48
CA2 P00918 2/20 0.46
CA4 P22748 1/20 0.46
CA5A P35218 1/20 0.46
RECQL P46063 1/20 0.45
TP53 P04637 1/20 0.44
EPHX1 P07099 1/20 0.44
TSHR P16473 1/20 0.44
EPHX2 P34913 1/20 0.44
CDK9 P50750 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
HTT P42858 1/20 0.44
IDO1 P14902 1/20 0.43
HPGD P15428 2/20 0.42
PTGS2 P35354 1/20 0.41
FDPS P14324 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL195068 0.84 CA9 (0.52) CA9CA12KDM4ENPSR1CA2
SCHEMBL9328080 0.82 CA9 (0.50) CA9CA12KDM4ENPSR1CA2
SCHEMBL5013978 0.80 CA9 (0.48) CA9CA12KDM4ENPSR1CA2
SCHEMBL8632209 0.80 NPSR1 (0.50) CA9CA12KDM4ENPSR1CA2
SCHEMBL6831560 0.80 CA9 (0.48) CA9CA12KDM4ENPSR1CA2
SCHEMBL730299 0.80 CA9 (0.48) CA9CA12KDM4ENPSR1CA2
SCHEMBL5169946 0.78 CA2 (0.52) CA9CA12KDM4ENPSR1CA2
SCHEMBL10797763 0.78 MEN1 (0.56) CA9CA12KDM4ENPSR1RECQL
Diphenylamine SCHEMBL27245439 0.76 HSD17B10 (0.67) CA9CA12CA2CA4CA5A
SCHEMBL1491874 0.76 NPSR1 (0.56) CA9CA12KDM4ENPSR1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000154277-A FLAME-RETARDANT RESIN COMPOSITION SHIKOKU CHEM CORP 2000-06-06 JP disclosed
EP-0120981-B1 RESIN ENCAPSULATION TYPE SEMICONDUCTOR DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 1988-10-12 EP disclosed
US-4617584-A GOOD HUMIDITY RESISTANCE, CORROSION RESITANCE; CURED NOVOLAC TYPE EPOXY RESIN, NOVOLAC PHENOLIC RESIN AND ORGANIC PHOSPHOROUS COMPOUND TOKYO SHIBAURA DENKI KABUSHIKI KAISHA (JP) 1986-10-14 US disclosed