SCHEMBL14918787

SCHEMBL14918787

C=CC(=O)c1ccccc1C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.64
ALOX15 P16050 1/20 0.64
AKT1 P31749 1/20 0.58
AKR1C3 P42330 1/20 0.50
KDM4E B2RXH2 3/20 0.48
HPGD P15428 3/20 0.48
HMGB1 P09429 2/20 0.48
NAPRT Q6XQN6 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA7 P43166 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
HSD17B10 Q99714 3/20 0.47
MAPT P10636 2/20 0.47
HDAC8 Q9BY41 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10347642 0.91 AKT1 (0.61) ALDH1A1ALOX15AKT1KDM4EHPGD
Phthalic Acid SCHEMBL29462501 0.86 ALDH1A1 (0.70) ALDH1A1ALOX15AKT1AKR1C3KDM4E
Phthalic Acid SCHEMBL335928 0.86 ALDH1A1 (0.70) ALDH1A1ALOX15AKT1AKR1C3KDM4E
Phthalic Acid SCHEMBL28696507 0.84 ALDH1A1 (0.67) ALDH1A1ALOX15AKT1AKR1C3KDM4E
Phthalic Acid SCHEMBL2316524 0.83 ALDH1A1 (0.74) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL28849612 0.83 ALDH1A1 (0.74) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL368383 0.83 ALDH1A1 (0.74) ALDH1A1ALOX15AKR1C3KDM4EHPGD
SCHEMBL28991884 0.83 AKT1 (0.54) ALDH1A1ALOX15AKT1KDM4EHPGD
SCHEMBL5452927 0.83 AKT1 (0.54) ALDH1A1ALOX15AKT1KDM4EHPGD
Benzene SCHEMBL11824173 0.83 MAPT (0.59) ALDH1A1ALOX15AKT1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250043047-A1 POLYMERIZABLE MONOMERS AND METHOD OF POLYMERIZING THE SAME ALIGN TECHNOLOGY INC (US) 2025-02-06 US disclosed
US-12152092-B2 Polymerizable monomers and method of polymerizing the same ALIGN TECHNOLOGY, INC. (US) 2024-11-26 US disclosed
CN-116640061-A Polymerizable monomer and polymerization method thereof 阿莱恩技术有限公司 2023-08-25 CN disclosed
CN-112074544-B Polymerizable monomer and polymerization method thereof 阿莱恩技术有限公司 2023-06-13 CN disclosed
CN-115068347-A Photocurable composition having excellent depth of cure 株式会社松风 2022-09-20 CN disclosed
CN-115068345-A Dental adhesive composition having excellent storage stability 株式会社松风 2022-09-20 CN disclosed
CN-114956672-A Semi-flexible asphalt and preparation method thereof 王志方 2022-08-30 CN disclosed
WO-2022138973-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2022-06-30 WO disclosed
WO-2022138972-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2022-06-30 WO disclosed
CN-113402666-A Dental photocurable composition with excellent color tone selectivity 株式会社松风 2021-09-17 CN disclosed
CN-113402665-A Dental photocurable composition comprising highly soluble photoacid generator 株式会社松风 2021-09-17 CN disclosed
CN-112074544-A Polymerizable monomer and polymerization method thereof 阿莱恩技术有限公司 2020-12-11 CN disclosed
US-20140275049-A1 SUBSTITUTED PYRAZOLE ANALOGS As RAR ANTAGONISTS ELI LILLY AND COMPANY 2014-09-18 US disclosed
WO-2013066640-A1 SUBSTITUTED PYRAZOLE ANALOGUES AS RAR ANTAGONISTS ELI LILLY AND COMPANY (US) 2013-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140275049-A1 SUBSTITUTED PYRAZOLE ANALOGS As RAR ANTAGONISTS RARB, RARA, RARG ALDH1A1 113/4885ALOX15 2333/4885AKT1 3930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.