Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347642 | 0.87 | AKT1 (0.61) | AKT1CYP3A4ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL14918787 | 0.83 | ALDH1A1 (0.64) | AKT1POLBCYP3A4ALDH1A1ALOX15 | |
| SCHEMBL1645158 | 0.82 | ALDH1A1 (0.58) | POLBCYP2C19ALDH1A1ALOX15KDM4E | |
| SCHEMBL28991884 | 0.79 | AKT1 (0.54) | AKT1CYP2C19CYP3A4ALDH1A1ALOX15 | |
| Vinyl Ether SCHEMBL8041439 | 0.78 | AKT1 (0.52) | AKT1CYP3A4ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL243558 | 0.78 | AKT1 (0.63) | AKT1CYP2C19CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL29540662 | 0.78 | AKT1 (0.63) | AKT1CYP2C19CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL28675532 | 0.77 | KDM4E (0.50) | AKT1POLBCYP3A4ALDH1A1ALOX15 | |
| SCHEMBL8865435 | 0.77 | AKT1 (0.50) | AKT1POLBCYP3A4ALDH1A1ALOX15 | |
| SCHEMBL7697862 | 0.77 | CYP3A4 (0.52) | AKT1CYP3A4ALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070242908-A1 | Forming Method of Dynamic Pressure Generating Portion and Fluid Dynamic Bearing Device | NTN CORPORATION (JP) | 2007-10-18 | — | — | US | disclosed |