Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | UNG | P13051 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14632341 | 0.81 | KDM4E (0.32) | ALDH1A1KDM4EHPGDENPP2HSD17B10 | |
| SCHEMBL27077695 | 0.76 | ALDH1A1 (0.43) | ALDH1A1ERN1KDM4EGAA | |
| SCHEMBL5173312 | 0.75 | — | — | |
| SCHEMBL10810993 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL69690 | 0.72 | KEAP1 (0.47) | ALDH1A1KDM4EHPGDENPP2HSD17B10 | |
| SCHEMBL257684 | 0.70 | — | — | |
| SCHEMBL4860925 | 0.69 | KDM5A (0.43) | ALDH1A1KDM4EHPGDENPP2HSD17B10 | |
| SCHEMBL4730848 | 0.68 | — | — | |
| SCHEMBL2491253 | 0.68 | — | — | |
| SCHEMBL31666384 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086395-A1 | NOVEL MICROORGANISM AND ITS USE IN LIGNOCELLULOSE DETOXIFICATION | SHELL OIL COMPANY | 2011-04-14 | — | — | US | disclosed |
| EP-2308959-A1 | Novel microorganism and its use in lignocellulose detoxifixcation | Shell Internationale Research Maatschappij B.V. (NL) | 2011-04-13 | — | — | EP | disclosed |
| WO-2011026906-A2 | NOVEL MICROORGANISM AND ITS USE IN LIGNOCELLULOSE DETOXIFICATION | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2011-03-10 | — | — | WO | disclosed |