SCHEMBL69690

SCHEMBL69690

O=C(O)c1cc[nH]c1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.47
NAPRT Q6XQN6 2/20 0.46
KDM4E B2RXH2 5/20 0.45
MAPT P10636 2/20 0.45
GAA P10253 1/20 0.45
ALDH1A1 P00352 5/20 0.43
ALOX15 P16050 1/20 0.43
CYP1A2 P05177 1/20 0.43
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.38
HPGD P15428 2/20 0.38
ENPP2 Q13822 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
HMGB1 P09429 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA7 P43166 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5653478 0.86 KEAP1 (0.41) KEAP1NAPRTKDM4EMAPTGAA
SCHEMBL311990 0.84 KEAP1 (0.40) KEAP1NAPRTKDM4EMAPTGAA
SCHEMBL29042806 0.81 RAB9A (0.41) KEAP1NAPRTKDM4EMAPTGAA
SCHEMBL27820698 0.81 CNR2 (0.42) KEAP1NAPRTKDM4EMAPTGAA
SCHEMBL10943013 0.78 AKR1C3 (0.55) KEAP1NAPRTKDM4EMAPTGAA
SCHEMBL27820699 0.78 NR4A2 (0.43) KDM4EMAPTGAAALDH1A1ALOX15
SCHEMBL5173312 0.77
SCHEMBL161489 0.77
SCHEMBL5174393 0.77
SCHEMBL5173735 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122089256-A Assembled hydraulic loop geological information system architecture 2026-05-26 CN claimed
CN-122048180-A Self-optimizing method and system for quality system based on PDCA (digital versatile framework) cycle 四川航泰航空装备有限公司 2026-05-15 CN claimed
CN-122022509-A Power industry management innovation system based on QC activity group 国网河南省电力公司襄城县供电公司 2026-05-12 CN claimed
US-12611384-B2 Antimicrobial nanoworms THE BOEING COMPANY (US) 2026-04-28 US claimed
CN-120059154-A In C4Method for producing polybutylene succinate polyester by taking unsaturated binary oxygen-containing compound as raw material 上海师范大学 2025-05-30 CN claimed
CN-119996281-A Industry digital router integrating AI digital ecology 上海司百袖信息技术有限公司 2025-05-13 CN claimed
CN-119894504-A Inhalable formulation for treating bacterial infections in the lungs 索米克生物技术有限公司 2025-04-25 CN claimed
CN-119863117-A Operation high risk identification and early warning method based on artificial intelligence technology 北京国网信通埃森哲信息技术有限公司 2025-04-22 CN claimed
CN-119809317-A Multidimensional risk factor index identification method based on artificial intelligence technology 北京国网信通埃森哲信息技术有限公司 2025-04-11 CN claimed
CN-119784122-A Sealing operation flow arrangement optimization method 辽宁理工职业大学 2025-04-08 CN claimed
CN-114077938-A Method and system for managing PDCA project 华晨宝马汽车有限公司 2022-02-22 CN claimed
WO-2022034357-A1 PROCESS FOR PREPARING SPHERICAL POLYMERIC PARTICLES FOR COSMETIC APPLICATION RHODIA BRASIL S.A. (BR) 2022-02-17 WO claimed
US-20200215208-A1 COMPOSITIONS COMPRISING MELANIN, AND METHODS OF PREPARING AND USES THEREOF RESEARCH & BUSINESS FOUNDATION, SUNGKYUNKWAN UNIVERSITY (KR) 2020-07-09 US claimed
US-20200181782-A1 ELECTROCHEMICAL REDUCTIVE CARBOXYLATION OF UNSATURATED ORGANIC SUBSTRATES IN IONICALLY CONDUCTIVE MEDIUMS BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2020-06-11 US claimed
WO-2019021035-A1 COMPOSITIONS COMPRISING MELANIN, AND METHODS OF PREPARING AND USES THEREOF MELANIS CO., LTD. (KR) 2019-01-31 WO claimed
WO-2019023532-A1 ELECTROCHEMICAL REDUCTIVE CARBOXYLATION OF UNSATURATED ORGANIC SUBSTRATES IN IONICALLY CONDUCTIVE MEDIUMS BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2019-01-31 WO claimed
US-8653048-B2 Prodrugs based on gemcitabine structure and synthetic methods and applications thereof SANLUGEN PHARMATECH LTD. (CN) 2014-02-18 US claimed
CN-102428093-A Prodrugs based on gemcitabine structure as well as synthetic method and application thereof SANLUGEN PHARMATECH LTD 2012-04-25 CN claimed
US-20120088908-A1 Prodrugs Based on Gemcitabine Structure and Synthetic Methods and Applications Thereof SANLUGEN PHARMATECH LTD. (CN) 2012-04-12 US claimed
EP-2423215-A1 PRODRUGS BASED ON GEMCITABINE STRUCTURE AS WELL AS SYNTHETIC METHOD AND APPLICATION THEREOF Sanlugen Pharmatech Ltd. (CN) 2012-02-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200215208-A1 COMPOSITIONS COMPRISING MELANIN, AND METHODS OF PREPARING AND USES THEREOF TYR, MCHR1, MCHR2 KEAP1 471/4885NAPRT 2833/4885KDM4E 3704/4885
US-20120088908-A1 Prodrugs Based on Gemcitabine Structure and Synthetic Methods and Applications Thereof TYMP, DCTD, GLS2 KEAP1 4836/4885NAPRT 671/4885KDM4E 2472/4885
US-12611384-B2 Antimicrobial nanoworms LCT, DNPEP, CLTA KEAP1 2017/4885NAPRT 1166/4885KDM4E 3213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.