Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14919481 | 0.87 | POLB (0.68) | POLBMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL14919972 | 0.86 | ALDH1A1 (0.71) | POLBMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL14919833 | 0.82 | TSHR (0.60) | POLBMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL14920008 | 0.81 | POLB (0.64) | POLBMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL14919801 | 0.81 | POLB (0.59) | POLBMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL14920079 | 0.81 | POLB (0.76) | POLBMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL14919795 | 0.81 | POLB (0.58) | POLBMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL14919916 | 0.80 | ALDH1A1 (0.61) | POLBMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL4470146 | 0.78 | MEN1 (0.71) | POLBMAPTALDH1A1HPGDTSHR | |
| SCHEMBL14919509 | 0.77 | KMT2A (0.65) | POLBMAPTALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066469-A2 | KINASE INHIBITORS CAPABLE OF INCREASING THE SENSITIVITY OF BACTERIAL PATHOGENS TO B-LACTAM ANTIBIOTICS | SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2013-05-10 | — | — | WO | disclosed |