Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527575 | 0.91 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL534911 | 0.87 | ALDH1A1 (0.47) | SLC6A3 | |
| SCHEMBL14920513 | 0.86 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16108739 | 0.85 | PDE4B (0.60) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16108740 | 0.85 | PDE4B (0.60) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14920294 | 0.85 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14920291 | 0.85 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14920936 | 0.84 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28466812 | 0.79 | ADAMTS5 (0.44) | — | |
| SCHEMBL14920363 | 0.77 | ADAMTS5 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773637-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064983-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2013-05-10 | — | — | WO | disclosed |