Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 17/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 14/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 14/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16108052 | 0.82 | DPP4 (0.49) | DPP4 | |
| SCHEMBL14934715 | 0.82 | DPP4 (0.49) | DPP4 | |
| SCHEMBL16108051 | 0.82 | DPP4 (0.49) | DPP4 | |
| SCHEMBL16141406 | 0.82 | DPP4 (0.49) | DPP4 | |
| SCHEMBL14920363 | 0.82 | ADAMTS5 (0.43) | — | |
| SCHEMBL2244051 | 0.81 | DPP4 (0.58) | DPP4DPP7DPP9DPP8CYP2D6 | |
| SCHEMBL5125043 | 0.81 | DPP4 (0.44) | DPP4DPP7DPP9DPP8CYP2D6 | |
| SCHEMBL17797332 | 0.79 | LMNA (0.38) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL15136612 | 0.77 | RAB9A (0.43) | — | |
| SCHEMBL3065638 | 0.77 | RAB9A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773637-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064983-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2013-05-10 | — | — | WO | disclosed |