Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | METAP1 | P53582 | 3/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.49 |
| ▸ | TYMS | P04818 | 3/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358939 | 0.89 | TDP1 (0.81) | TDP1L3MBTL1METAP1PARP1PARP10 | |
| SCHEMBL14925847 | 0.89 | METAP1 (0.60) | TDP1L3MBTL1METAP1PARP1PARP10 | |
| SCHEMBL22797539 | 0.81 | TDP1 (0.77) | TDP1L3MBTL1METAP1PARP1PARP10 | |
| SCHEMBL5676610 | 0.81 | S100A4 (0.68) | TDP1L3MBTL1ELANES100A4MAOA | |
| SCHEMBL28531047 | 0.81 | ELANE (0.67) | ELANES100A4MAOAMAOBACHE | |
| SCHEMBL7052871 | 0.80 | TDP1 (1.00) | TDP1L3MBTL1METAP1PARP1PARP10 | |
| SCHEMBL8797457 | 0.80 | TDP1 (0.64) | TDP1L3MBTL1METAP1PARP1PARP10 | |
| SCHEMBL21234894 | 0.79 | METAP1 (0.55) | TDP1L3MBTL1METAP1PARP1PARP10 | |
| SCHEMBL30832101 | 0.79 | MIF (0.66) | TDP1L3MBTL1MAOAMAOBCYP19A1 | |
| SCHEMBL8954148 | 0.78 | S100A4 (0.63) | ELANES100A4MAOAMAOBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130112965-A1 | ORGANIC LIGHT-EMITTING DEVICE MATERIAL HAVING DIBENZOSUBERONE SKELETON | CANON KABUSHIKI KAISHA (JP) | 2013-05-09 | — | — | US | disclosed |