SCHEMBL14925847

SCHEMBL14925847

Cc1ccc2c(c1)C(=O)c1cc(C)ccc1CC2

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 3/20 0.60
PARP10 Q53GL7 2/20 0.58
PARP1 P09874 1/20 0.58
ELANE P08246 1/20 0.54
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
ACHE P22303 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TYMS P04818 1/20 0.47
CYP19A1 P11511 4/20 0.46
CYP11B2 P19099 2/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA4 P22748 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
ALDH1A1 P00352 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
PARP11 Q9NR21 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8797457 0.90 TDP1 (0.64) METAP1PARP10PARP1ELANEMAOA
SCHEMBL21234894 0.90 METAP1 (0.55) METAP1PARP10PARP1ELANEMAOA
SCHEMBL14925865 0.89 TDP1 (0.67) METAP1PARP10PARP1ELANEMAOA
SCHEMBL1609651 0.86 METAP1 (0.71) METAP1PARP10PARP1ELANEMAOA
SCHEMBL19416655 0.86 METAP1 (0.71) METAP1PARP10PARP1ELANEMAOA
SCHEMBL6056920 0.84 METAP1 (0.69) METAP1PARP10PARP1ELANEMAOA
SCHEMBL354988 0.84 PBRM1 (0.59) METAP1PARP10PARP1ELANEMAOA
SCHEMBL30465799 0.84 PBRM1 (0.59) METAP1PARP10PARP1ELANEMAOA
SCHEMBL4135391 0.84 METAP1 (0.50) METAP1PARP10PARP1ELANEMAOA
SCHEMBL4151697 0.84 CASP1 (0.54) METAP1PARP10PARP1ELANEMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020248943-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2020-12-17 WO disclosed
US-20130112965-A1 ORGANIC LIGHT-EMITTING DEVICE MATERIAL HAVING DIBENZOSUBERONE SKELETON CANON KABUSHIKI KAISHA (JP) 2013-05-09 US disclosed