SCHEMBL14926673

SCHEMBL14926673

Cc1ccc(N=Nc2ccc(C)c(F)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.44
NPC1 O15118 9/20 0.44
RAB9A P51151 8/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
MAPK1 P28482 2/20 0.44
PKM P14618 1/20 0.44
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 3/20 0.42
STAT3 P40763 1/20 0.42
STAT1 P42224 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HTT P42858 2/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
KMT2A Q03164 8/20 0.40
MEN1 O00255 6/20 0.40
ALDH1A1 P00352 2/20 0.40
USP2 O75604 2/20 0.40
HSP90AA1 P07900 1/20 0.40
HTR3E A5X5Y0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14926688 1.00 MAPT (0.44) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL14926697 0.94 MAPT (0.45) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL14926680 0.91 MAPT (0.46) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL14926685 0.85 MAPT (0.42) MAPTNPC1RAB9AMAPK1TDP1
SCHEMBL14930554 0.82 KMT2A (0.54) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL18590730 0.82 KMT2A (0.47) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL18590719 0.80 NPC1 (0.48) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL14926676 0.80 NPC1 (0.48) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL14926693 0.80 NPC1 (0.48) MAPTNPC1RAB9AL3MBTL1MAPK1
SCHEMBL18590734 0.80 MAPT (0.40) MAPTNPC1RAB9AMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210191170-A1 OPTICAL DEVICE AND REFRESH DRIVING METHOD FOR OPTICAL DEVICE KYOTO UNIVERSITY (JP) 2021-06-24 US disclosed
US-10914987-B2 Complex and optical element KYOTO UNIVERSITY (JP) 2021-02-09 US disclosed
US-20200241336-A1 COMPLEX AND OPTICAL ELEMENT KYOTO UNIVERSITY (JP) 2020-07-30 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
EP-2727947-B1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING HARDENED PRODUCT THEREOF DAINIPPON INK & CHEMICALS (JP) 2017-03-15 EP disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
EP-2727947-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING HARDENED PRODUCT THEREOF DIC Corporation (JP) 2014-05-07 EP disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed