SCHEMBL14930554

SCHEMBL14930554

Cc1cccc(N=Nc2ccc(C)c(F)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.54
MEN1 O00255 8/20 0.54
NPC1 O15118 7/20 0.54
RAB9A P51151 6/20 0.54
CASP3 P42574 2/20 0.54
SENP8 Q96LD8 2/20 0.54
SENP7 Q9BQF6 2/20 0.54
SENP6 Q9GZR1 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
NSD2 O96028 1/20 0.54
HTR3E A5X5Y0 2/20 0.47
HTR3B O95264 2/20 0.47
HTR3A P46098 2/20 0.47
HTR3D Q70Z44 2/20 0.47
HTR3C Q8WXA8 2/20 0.47
MAPT P10636 9/20 0.43
MAPK1 P28482 4/20 0.43
POLB P06746 1/20 0.43
GFER P55789 1/20 0.43
ACHE P22303 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14926680 0.86 MAPT (0.46) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL14926697 0.84 MAPT (0.45) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL14926673 0.82 MAPT (0.44) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL14926688 0.82 MAPT (0.44) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL30332449 0.82 MEN1 (0.67) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL1405327 0.82 MEN1 (0.67) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL30102207 0.82 MEN1 (0.67) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL11981455 0.82 MEN1 (0.67) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL1405329 0.82 MEN1 (0.67) KMT2AMEN1NPC1RAB9ACASP3
SCHEMBL14926685 0.80 MAPT (0.42) KMT2AMEN1NPC1RAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed