SCHEMBL14926697

SCHEMBL14926697

Cc1ccc(N=Nc2ccc(N=Nc3ccc(C)c(F)c3)cc2)cc1F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.45
HTT P42858 2/20 0.45
TSHR P16473 2/20 0.45
HSD17B10 Q99714 1/20 0.45
KMT2A Q03164 9/20 0.40
NPC1 O15118 8/20 0.40
RAB9A P51151 8/20 0.40
MEN1 O00255 8/20 0.40
KDM4E B2RXH2 1/20 0.40
USP2 O75604 1/20 0.40
BLM P54132 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
ACHE P22303 1/20 0.39
HDAC1 Q13547 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
TDP1 Q9NUW8 4/20 0.37
NSD2 O96028 1/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14926680 0.98 MAPT (0.46) MAPTHTTTSHRHSD17B10KMT2A
SCHEMBL14926673 0.94 MAPT (0.44) MAPTHTTTSHRHSD17B10KMT2A
SCHEMBL14926688 0.94 MAPT (0.44) MAPTHTTTSHRHSD17B10KMT2A
SCHEMBL14926685 0.91 MAPT (0.42) MAPTHTTTSHRHSD17B10KMT2A
SCHEMBL18590734 0.85 MAPT (0.40) MAPTHTTTSHRHSD17B10KMT2A
SCHEMBL18590740 0.85 MAPT (0.41) MAPTHTTTSHRHSD17B10KMT2A
SCHEMBL14930554 0.84 KMT2A (0.54) MAPTHTTTSHRHSD17B10KMT2A
SCHEMBL14926682 0.82 MAPT (0.50) MAPTHTTTSHRHSD17B10KMT2A
SCHEMBL27733750 0.79 MAPT (0.44) MAPTHTTTSHRHSD17B10KMT2A
SCHEMBL11857540 0.79 MAPT (0.47) MAPTHTTTSHRHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210191170-A1 OPTICAL DEVICE AND REFRESH DRIVING METHOD FOR OPTICAL DEVICE KYOTO UNIVERSITY (JP) 2021-06-24 US disclosed
US-10914987-B2 Complex and optical element KYOTO UNIVERSITY (JP) 2021-02-09 US disclosed
US-20200241336-A1 COMPLEX AND OPTICAL ELEMENT KYOTO UNIVERSITY (JP) 2020-07-30 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed