SCHEMBL14926686

SCHEMBL14926686

COc1cc(N=Nc2ccc(C)c(C)c2)ccc1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.49
KMT2A Q03164 6/20 0.49
NPC1 O15118 4/20 0.44
RAB9A P51151 4/20 0.44
PTGS2 P35354 2/20 0.44
PTGS1 P23219 2/20 0.44
GAA P10253 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
HSP90AA1 P07900 2/20 0.44
BRD4 O60885 1/20 0.41
HTR3E A5X5Y0 1/20 0.40
HTR3B O95264 1/20 0.40
HTR3A P46098 1/20 0.40
HTR3D Q70Z44 1/20 0.40
HTR3C Q8WXA8 1/20 0.40
TUBB1 Q9H4B7 3/20 0.40
MAPT P10636 4/20 0.38
NPSR1 Q6W5P4 1/20 0.38
AGTR1 P30556 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14926701 0.98 MEN1 (0.47) MEN1KMT2ANPC1RAB9APTGS2
SCHEMBL14930552 0.94 MEN1 (0.49) MEN1KMT2ANPC1RAB9APTGS2
SCHEMBL14930478 0.92 PTGS2 (0.50) MEN1KMT2ANPC1RAB9APTGS2
SCHEMBL14930444 0.86 PTGS2 (0.46) MEN1KMT2ANPC1RAB9APTGS2
SCHEMBL14930525 0.86 PTGS2 (0.46) MEN1KMT2ANPC1RAB9APTGS2
SCHEMBL14926684 0.83 HTR3E (0.42) MEN1KMT2ANPC1RAB9APTGS2
SCHEMBL14926682 0.83 MAPT (0.50) MEN1KMT2ANPC1RAB9APTGS2
SCHEMBL11516839 0.82 KMT2A (0.45) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL11516843 0.82 KMT2A (0.45) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL31264508 0.82 KMT2A (0.45) MEN1KMT2ANPC1RAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed