SCHEMBL14926682

SCHEMBL14926682

COc1cc(N=Nc2ccc(C)c(F)c2)ccc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
PTGS2 P35354 2/20 0.41
PTGS1 P23219 2/20 0.41
GAA P10253 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
NPC1 O15118 1/20 0.41
HSP90AA1 P07900 1/20 0.41
RAB9A P51151 1/20 0.41
TUBB1 Q9H4B7 2/20 0.39
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
EGFR P00533 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14930552 0.89 MEN1 (0.49) MAPTMEN1KMT2APTGS2PTGS1
SCHEMBL14930478 0.87 PTGS2 (0.50) MAPTMEN1KMT2APTGS2PTGS1
SCHEMBL14926680 0.84 MAPT (0.46) MAPTMEN1KMT2AL3MBTL1NPC1
SCHEMBL14926686 0.83 MEN1 (0.49) MAPTMEN1KMT2APTGS2PTGS1
SCHEMBL14926697 0.82 MAPT (0.45) MAPTMEN1KMT2AL3MBTL1NPC1
SCHEMBL14930444 0.81 PTGS2 (0.46) MAPTMEN1KMT2APTGS2PTGS1
SCHEMBL14926701 0.81 MEN1 (0.47) MAPTMEN1KMT2APTGS2PTGS1
SCHEMBL14930525 0.81 PTGS2 (0.46) MAPTMEN1KMT2APTGS2PTGS1
SCHEMBL14926685 0.79 MAPT (0.42) MAPTMEN1KMT2ANPC1HSP90AA1
SCHEMBL14926684 0.79 HTR3E (0.42) MAPTMEN1KMT2APTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210191170-A1 OPTICAL DEVICE AND REFRESH DRIVING METHOD FOR OPTICAL DEVICE KYOTO UNIVERSITY (JP) 2021-06-24 US disclosed
US-10914987-B2 Complex and optical element KYOTO UNIVERSITY (JP) 2021-02-09 US disclosed
US-20200241336-A1 COMPLEX AND OPTICAL ELEMENT KYOTO UNIVERSITY (JP) 2020-07-30 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
WO-2017034023-A1 COMPLEX AND OPTICAL ELEMENT 国立大学法人京都大学 2017-03-02 WO disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed