Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930654 | 0.84 | EGFR (0.39) | HTTKDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL128882 | 0.82 | HTT (0.41) | HTTKDM4ESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL14927083 | 0.81 | HTT (0.40) | HTTKDM4ESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL16510442 | 0.77 | SMN1; SMN2 (0.40) | HTTKDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL14926973 | 0.75 | HTT (0.37) | HTTKDM4ESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL16383319 | 0.70 | ACACA (0.38) | KDM4ESMN1; SMN2ALDH1A1RAB9AMEN1 | |
| SCHEMBL14927009 | 0.69 | MEN1 (0.42) | KDM4ESMN1; SMN2ADORA2AALDH1A1POLB | |
| SCHEMBL16189623 | 0.69 | RAC1 (0.40) | HTTKDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL16383156 | 0.67 | EGFR (0.39) | HTTKDM4ESMN1; SMN2ALDH1A1POLB | |
| Iodide SCHEMBL14916506 | 0.66 | EGFR (0.39) | HTTKDM4ESMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | MRPL21, ARG1, RPP30 | HTT 3827/4885KDM4E 2572/4885SMN1; SMN2 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.