Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RAC1 | P63000 | 2/20 | 0.34 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | WHR1 | P49842 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930654 | 0.83 | EGFR (0.39) | ACACAEGFRMEN1KMT2ANPC1 | |
| SCHEMBL14926982 | 0.83 | CD274 (0.45) | CD274PDCD1 | |
| SCHEMBL16510442 | 0.82 | SMN1; SMN2 (0.40) | ACACAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16510678 | 0.78 | PDE10A (0.37) | ACHE | |
| SCHEMBL12070517 | 0.75 | USP2 (0.44) | ACACACD274PDCD1MEN1KMT2A | |
| SCHEMBL14926990 | 0.73 | PDE4A (0.38) | — | |
| SCHEMBL13334283 | 0.72 | KDM4E (0.44) | ACACAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16510600 | 0.70 | KDM4E (0.40) | ACACAMEN1KMT2ARAC1LMNA | |
| SCHEMBL14927012 | 0.70 | HTT (0.38) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL13076590 | 0.70 | ALDH1A1 (0.41) | ACACAEGFRMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |
| WO-2011156626-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-15 | — | — | WO | disclosed |