Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1492728 | 0.84 | CYP2C19 (0.50) | MAPTALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL28727593 | 0.82 | CYP2C19 (0.48) | MAPTALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL28938744 | 0.82 | CYP2C19 (0.48) | MAPTALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL9432011 | 0.81 | CYP1A2 (0.40) | MAPTHPGDRAB9AALDH1A1HDAC1 | |
| SCHEMBL28729111 | 0.80 | CYP2C19 (0.47) | MAPTALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL8494650 | 0.78 | SMN1; SMN2 (0.47) | MAPTRAB9AALDH1A1HDAC3HDAC1 | |
| SCHEMBL27934590 | 0.78 | ALDH1A1 (0.49) | HPGDRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL9473731 | 0.77 | ALDH1A1 (0.52) | MAPTGAAHPGDRAB9AALDH1A1 | |
| SCHEMBL28915433 | 0.77 | NPC1 (0.46) | MAPTGAAHPGDRAB9AALDH1A1 | |
| SCHEMBL8148677 | 0.77 | ESR1 (0.52) | HPGDALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290936-A | Indicators or labels for antibodies or medical diagnosis | LONDON DIAGNOSTICS, INC. (US) | 1994-03-01 | — | — | US | disclosed |
| US-5284951-A | Aryl ester, thioester or amide of carboxylic acid substituted heterocyclic ring; quaternary compounds | LONDON DIAGNOSTICS, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| US-5283334-A | Side-chain functional chemiluminescent labels and their conjugates, and assays therefrom | LONDON DIAGNOSTICS, INC. (US) | 1994-02-01 | — | — | US | disclosed |