SCHEMBL14928248

SCHEMBL14928248

CC1(C)c2ccccc2-c2ccc3c4ccccc4n(-c4ccc(Br)cc4)c3c21

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DUSP3 P51452 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
RXFP1 Q9HBX9 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
PGR P06401 1/20 0.30
HSP90AA1 P07900 1/20 0.30
IDO1 P14902 1/20 0.30
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30
HTT P42858 1/20 0.30
ALKBH5 Q6P6C2 1/20 0.30
FTO Q9C0B1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17245709 0.92 KDM4E (0.41) DUSP3KDM4EATML3MBTL1PGR
SCHEMBL10014056 0.90 KDM4E (0.45) DUSP3KDM4EATML3MBTL1PGR
SCHEMBL14928215 0.90 PDK2 (0.34) DUSP3
SCHEMBL15871201 0.90 PDK2 (0.34) DUSP3
SCHEMBL23225656 0.89 PGR (0.41) DUSP3KDM4EATML3MBTL1PGR
SCHEMBL10014058 0.89 KDM4E (0.38) DUSP3KDM4EATML3MBTL1PGR
SCHEMBL16406819 0.88 DUSP3 (0.34) DUSP3KDM4EATML3MBTL1PGR
SCHEMBL17245687 0.88 L3MBTL1 (0.37) DUSP3KDM4EATML3MBTL1PGR
SCHEMBL1755431 0.88 KMT2A (0.36) DUSP3KDM4EATML3MBTL1PGR
SCHEMBL15434266 0.88 KDM4E (0.42) DUSP3KDM4EATML3MBTL1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150115205-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-04-30 US disclosed
US-20150115205-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-04-30 US disclosed
US-8828559-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-09-09 US disclosed
US-8828559-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-09-09 US disclosed
US-20140061609-A1 NOVEL COMPOUNDS FOR ORGANIC ELECTRONIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2014-03-06 US disclosed
US-20140061609-A1 NOVEL COMPOUNDS FOR ORGANIC ELECTRONIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2014-03-06 US disclosed
WO-2013165189-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2013-11-07 WO disclosed
US-20130113367-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-05-09 US disclosed
US-20130113367-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130113367-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME TELO2, ARL1, CRY1 DUSP3 4828/4885KDM4E 2160/4885ATM 2336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.