SCHEMBL14928286

SCHEMBL14928286

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nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
KDM4E B2RXH2 2/20 0.37
PDE4A P27815 1/20 0.32
THRB P10828 1/20 0.32
MGAM O43451 1/20 0.30
SI P14410 1/20 0.30
USP2 O75604 1/20 0.30
SLCO1B1 Q9Y6L6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14866617 0.82 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL8025665 0.80 LMNA (0.38) LMNAL3MBTL1TDP1KDM4ETHRB
SCHEMBL9300148 0.80 LMNA (0.38) LMNAL3MBTL1TDP1KDM4ETHRB
Xylitol SCHEMBL2983122 0.79 LMNA (0.57) LMNAL3MBTL1TDP1KDM4EPDE4A
Sorbitol SCHEMBL247059 0.79 LMNA (0.57) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL11105758 0.79 LMNA (0.57) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL20234405 0.79 LMNA (0.46) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL20296909 0.78 LMNA (0.36) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL20296908 0.78 LMNA (0.36) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL14363640 0.76 LMNA (0.48) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130115627-A1 METHODS FOR IDENTIFYING CANDIDATE CYTOTOXIC ANTIBODY MOLECULES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-05-09 US disclosed