Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300148 | 0.94 | LMNA (0.38) | LMNATHRBL3MBTL1TDP1KDM4E | |
| SCHEMBL14866617 | 0.85 | LMNA (0.50) | LMNATHRBL3MBTL1TDP1KDM4E | |
| SCHEMBL12929271 | 0.84 | THRB (0.31) | LMNATHRBL3MBTL1 | |
| SCHEMBL12928872 | 0.84 | CYP2D6 (0.39) | LMNATHRBL3MBTL1KDM4EMGAM | |
| SCHEMBL12928873 | 0.84 | LMNA (0.35) | LMNATHRBL3MBTL1TDP1 | |
| SCHEMBL14928286 | 0.80 | LMNA (0.43) | LMNATHRBL3MBTL1TDP1KDM4E | |
| SCHEMBL12928866 | 0.80 | — | — | |
| SCHEMBL3441481 | 0.80 | AKR1B1 (0.34) | — | |
| SCHEMBL9443589 | 0.78 | LMNA (0.38) | LMNATHRBL3MBTL1TDP1KDM4E | |
| SCHEMBL14668317 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096692-A | CYLIC KETALS AND ACDTALS HAVING HEAT AND OXIDATION RESISTANCE, ARE FREE FROM CARBOXYLIC ACIDS FORMING DUE TO HYDROLYSIS, LOW IN HYGROSCOPICITY, INEXPENSIVE, GOOD INSULATION AND COMPATIBLE WITH HYDROFLUOROCARBONS; WORKING FLUID REFRIGERANTS | KAO CORPORATION (JP) | 2000-08-01 | — | — | US | disclosed |
| CN-1161693-A | Synthetic lubricating oil | KAO CORP (JP) | 1997-10-08 | — | — | CN | disclosed |
| EP-0779289-A1 | SYNTHETIC LUBRICATING OIL | Kao Corporation (JP) | 1997-06-18 | — | — | EP | disclosed |