Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025665 | 0.94 | LMNA (0.38) | LMNATHRBL3MBTL1TDP1KDM4E | |
| SCHEMBL12929271 | 0.89 | THRB (0.31) | LMNATHRBL3MBTL1 | |
| SCHEMBL14866617 | 0.85 | LMNA (0.50) | LMNATHRBL3MBTL1TDP1KDM4E | |
| SCHEMBL12928873 | 0.84 | LMNA (0.35) | LMNATHRBL3MBTL1TDP1 | |
| SCHEMBL12928872 | 0.84 | CYP2D6 (0.39) | LMNATHRBL3MBTL1KDM4EMGAM | |
| SCHEMBL14928286 | 0.80 | LMNA (0.43) | LMNATHRBL3MBTL1TDP1KDM4E | |
| SCHEMBL3441481 | 0.80 | AKR1B1 (0.34) | — | |
| SCHEMBL12928866 | 0.80 | — | — | |
| SCHEMBL9443589 | 0.78 | LMNA (0.38) | LMNATHRBL3MBTL1TDP1KDM4E | |
| SCHEMBL14668317 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884202-B2 | Nucleobases are perfluoroalkylated in a one step process with a perfluoroalkyl halide in the presence of a sulfoxide, a peroxide and an iron compound; useful as medicinal drugs, intermediates for medicinal drugs and agricultural chemicals | TOSOH CORPORATION (JP) | 2011-02-08 | — | — | US | disclosed |
| US-5276174-A | Alk-1-enyloxy carbonates | ISP INVESTMENTS INC. (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0514482-A4 | VINYL ETHER COMPOUNDS | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0514482-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1992-11-25 | — | — | EP | disclosed |
| WO-1991013052-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1991-09-05 | — | — | WO | disclosed |