SCHEMBL14928843

SCHEMBL14928843

CCOC(=O)c1cc(C2(c3ccc(C)c(CCOC=O)c3)c3cc(C)ccc3-c3ccc(C)cc32)ccc1OCCCNC

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPK1 P28482 2/20 0.33
KDM4E B2RXH2 5/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL4 Q8NA19 1/20 0.32
L3MBTL3 Q96JM7 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 2/20 0.31
HSP90AA1 P07900 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
LMNA P02545 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14928851 0.89 CYP1A2 (0.34) ALDH1A1L3MBTL1TDP1MAPK1KDM4E
SCHEMBL14929049 0.86 ALDH1A1 (0.41) ALDH1A1L3MBTL1TDP1KDM4EMEN1
SCHEMBL10348142 0.81 ALDH1A1 (0.36) ALDH1A1L3MBTL1TDP1KDM4EMEN1
SCHEMBL14929089 0.81
SCHEMBL10348298 0.81 TDP1 (0.33) ALDH1A1L3MBTL1TDP1KDM4EMEN1
SCHEMBL12924833 0.80 L3MBTL1 (0.37) ALDH1A1L3MBTL1TDP1MAPK1MEN1
SCHEMBL10348158 0.80 ALDH1A1 (0.35) ALDH1A1L3MBTL1TDP1KDM4EMEN1
SCHEMBL14928838 0.80 MEN1 (0.31) MEN1KMT2A
SCHEMBL10348402 0.79 L3MBTL4 (0.34) ALDH1A1L3MBTL1TDP1KDM4EMEN1
SCHEMBL10348418 0.79 ALDH1A1 (0.35) ALDH1A1L3MBTL1TDP1KDM4EL3MBTL4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8963422-B2 Method for manufacturing organic light-emitting device and organic light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-24 US disclosed
US-20130112966-A1 METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-09 US disclosed