Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.54 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930466 | 0.92 | ALDH1A1 (0.60) | PDE3BPDE3AP2RY12ALDH1A1L3MBTL1 | |
| SCHEMBL14926506 | 0.90 | PDE3B (0.54) | PDE3BPDE3AP2RY12ALDH1A1L3MBTL1 | |
| SCHEMBL14926509 | 0.90 | ALDH1A1 (0.58) | PDE3BPDE3AP2RY12ALDH1A1THRA | |
| SCHEMBL14926513 | 0.89 | THRA (0.56) | PDE3BPDE3AP2RY12ALDH1A1THRA | |
| SCHEMBL14926512 | 0.89 | THRA (0.56) | PDE3BPDE3AP2RY12ALDH1A1THRA | |
| SCHEMBL14926510 | 0.89 | THRA (0.56) | PDE3BPDE3AP2RY12ALDH1A1THRA | |
| SCHEMBL14930467 | 0.89 | THRA (0.56) | PDE3BPDE3AP2RY12ALDH1A1THRA | |
| SCHEMBL14926511 | 0.89 | PDE3B (0.53) | PDE3BPDE3AP2RY12ALDH1A1L3MBTL1 | |
| SCHEMBL18643843 | 0.89 | KDM4E (0.46) | PDE3BPDE3AP2RY12ALDH1A1AKR1C3 | |
| SCHEMBL14926504 | 0.86 | THRA (0.53) | PDE3BPDE3AP2RY12ALDH1A1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130116396-A1 | POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER | DIC CORPORATION (JP) | 2013-05-09 | — | — | US | disclosed |