Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930523 | 0.89 | PDE3B (0.54) | KDM4ELMNAMAPTPDE3BPDE3A | |
| SCHEMBL19722617 | 0.84 | LMNA (0.47) | KDM4ENPC1LMNATP53CYP1A2 | |
| SCHEMBL14445681 | 0.82 | HDAC1 (0.56) | CYP1A2 | |
| SCHEMBL14930466 | 0.81 | ALDH1A1 (0.60) | TP53MAOAPDE3BPDE3AP2RY12 | |
| SCHEMBL14926506 | 0.80 | PDE3B (0.54) | MAOAPDE3BPDE3AP2RY12ALDH1A1 | |
| SCHEMBL14926509 | 0.80 | ALDH1A1 (0.58) | TP53MAOAPDE3BPDE3AP2RY12 | |
| SCHEMBL13422217 | 0.79 | PPARA (0.48) | ALDH1A1PPARGPPARA | |
| SCHEMBL14926504 | 0.79 | THRA (0.53) | TP53MAOAPDE3BPDE3AP2RY12 | |
| SCHEMBL14926510 | 0.79 | THRA (0.56) | TP53MAOAPDE3BPDE3AP2RY12 | |
| SCHEMBL14926513 | 0.79 | THRA (0.56) | TP53MAOAPDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2727947-B1 | COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING HARDENED PRODUCT THEREOF | DAINIPPON INK & CHEMICALS (JP) | 2017-03-15 | — | — | EP | disclosed |