SCHEMBL14930528

SCHEMBL14930528

COCCOc1ccc2cc(OC(F)(F)F)ccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CBFB Q13951 1/20 0.53
KDM4E B2RXH2 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
MAPK1 P28482 1/20 0.44
PIM1 P11309 2/20 0.43
CHRM5 P08912 2/20 0.41
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
MIF P14174 1/20 0.40
PPARG P37231 1/20 0.40
FFAR4 Q5NUL3 2/20 0.40
GPR3 P46089 1/20 0.40
NPC1 O15118 1/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ABL1 P00519 1/20 0.39
FFAR1 O14842 1/20 0.38
CYP17A1 P05093 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18834265 0.86 PIM1 (0.51) CBFBKDM4EMAPK1PIM1CHRM5
SCHEMBL14232317 0.81 KDM4E (0.47) KDM4ETDP1MAPK1KMT2AMIF
SCHEMBL14930469 0.81 HRH2 (0.46) CBFBKDM4ETDP1PIM1FFAR4
SCHEMBL14930514 0.81 HRH2 (0.46) CBFBKDM4ETDP1PIM1FFAR4
SCHEMBL14930516 0.80 CYP1A2 (0.54) KDM4ETDP1MAPK1KMT2APPARG
SCHEMBL7661606 0.79 CA12 (0.43) CBFBKDM4ETDP1MAPK1FFAR4
SCHEMBL7659967 0.79 CA12 (0.43) FFAR4FFAR1PPM1A
SCHEMBL14926621 0.79 MIF (0.50) KDM4ETDP1MAPK1MIFPPARG
SCHEMBL14926623 0.78 KDM4E (0.53) KDM4ETDP1MAPK1NPC1MAPT
SCHEMBL2214606 0.78 KDM4E (0.71) KDM4ETDP1MAPK1PPARGNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9939555-B2 Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof DIC CORPORATION (JP) 2018-04-10 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
US-20160274418-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2016-09-22 US disclosed
US-9360708-B2 Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof DIC CORPORATION (JP) 2016-06-07 US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20140154428-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-06-05 US disclosed
EP-2727903-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING HARDENED PRODUCT OF SAID POLYMER DIC Corporation (JP) 2014-05-07 EP disclosed
US-20140121345-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-05-01 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed