SCHEMBL1493053

SCHEMBL1493053

O=C=Nc1ccc(OCCCOc2ccc(N=C=O)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.52
TSHR P16473 1/20 0.52
FURIN P09958 2/20 0.50
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP1A2 P05177 2/20 0.39
CYP19A1 P11511 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
TMPRSS2 O15393 1/20 0.38
KCNA3 P22001 1/20 0.38
PPARA Q07869 1/20 0.37
PRSS1 P07477 2/20 0.37
DRD2 P14416 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10341873 0.96 CYP3A4 (0.52) CYP3A4TSHRFURINMAPK1TDP1
SCHEMBL7602206 0.94 TSHR (0.50) CYP3A4TSHRFURINL3MBTL1TMPRSS2
SCHEMBL10703892 0.94 TSHR (0.50) CYP3A4TSHRFURINL3MBTL1TMPRSS2
SCHEMBL10341829 0.94 CYP3A4 (0.54) CYP3A4TSHRFURINALDH1A1MAPT
SCHEMBL414168 0.90 CYP1A2 (0.50) CYP3A4TSHRLMNACYP1A2CYP19A1
SCHEMBL7898652 0.89 TSHR (0.46) CYP3A4TSHRFURINL3MBTL1TMPRSS2
SCHEMBL13264902 0.88 TSHR (0.48) CYP3A4TSHRFURINMAPTSMN1; SMN2
SCHEMBL991987 0.86 CYP2C9 (0.50) CYP3A4TSHRALDH1A1LMNAMAPT
SCHEMBL27594985 0.86 ALDH1A1 (0.48) CYP3A4TSHRFURINALDH1A1SMN1; SMN2
SCHEMBL3707532 0.86 NR5A1 (0.54) TSHRLMNAMAPTGAAPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111868617-B Liquid crystal aligning agent, polymer for obtaining the same, liquid crystal alignment film, and liquid crystal display element using the same 日产化学株式会社 2023-09-12 CN disclosed
US-9153843-B2 Negative electrode including solid electrolyte interface coating containing crosslinked isocyanate compound, nonaqueous electrolyte secondary battery and method for manufacturing the same SONY CORPORATION (JP) 2015-10-06 US disclosed
US-20110052953-A1 NEGATIVE ELECTRODE, NONAQUEOUS ELECTROLYTE SECONDARY BATTERY AND METHOD FOR MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-03-03 US disclosed
US-4888125-A Diisocyanates, a process for their production and their use in the production of polyurethane plastics BAYER AKTIENGESELLSCHAFT (DE) 1989-12-19 US disclosed
EP-0183115-B1 BIS(4-ISOCYANATOPHENOXY) ALKANES OPTIONALLY METHYL-SUBSTITUTED IN POSITION 3, METHOD FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF POLYURETHANES BAYER AG (DE) 1988-06-01 EP disclosed