SCHEMBL1493083

SCHEMBL1493083

C=CC[SiH](C=C)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
MMP9 P14780 2/20 0.31
CYP2C19 P33261 1/20 0.31
IDH1 O75874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15902562 0.83 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL21527924 0.82 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL9637408 0.79
SCHEMBL27841202 0.77 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL444984 0.77 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL216362 0.76 ALDH1A1 (0.36) ALDH1A1TSHRCYP2C19
SCHEMBL860549 0.76 CYP2C19 (0.36) ALDH1A1TSHRMMP9CYP2C19
Fluoride SCHEMBL27912992 0.74 CYP2C19 (0.35) ALDH1A1TSHRMMP9CYP2C19
SCHEMBL7198219 0.74 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL27895965 0.74 ALDH1A1 (0.31) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2470574-B1 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORP (JP) 2014-09-17 EP claimed
US-8765887-B2 Process and catalyst system for polydiene production BRIDGESTONE CORPORATION (JP) 2014-07-01 US claimed
EP-2470574-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION Bridgestone Corporation (JP) 2012-07-04 EP claimed
US-20120165484-A1 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2012-06-28 US claimed
WO-2011028523-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2011-03-10 WO claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed
US-11767388-B1 Silicon-functionalized rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2023-09-26 US disclosed
EP-2470574-B1 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORP (JP) 2014-09-17 EP disclosed
US-8765887-B2 Process and catalyst system for polydiene production BRIDGESTONE CORPORATION (JP) 2014-07-01 US disclosed
EP-2470574-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION Bridgestone Corporation (JP) 2012-07-04 EP disclosed
US-20120165484-A1 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2012-06-28 US disclosed
WO-2011028523-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2011-03-10 WO disclosed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US disclosed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US disclosed