SCHEMBL216362

SCHEMBL216362

C=CC[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
TSHR P16473 2/20 0.36
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.31
AKT1 P31749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL860549 0.80 CYP2C19 (0.36) ALDH1A1TSHRCYP2C19HTTAKT1
SCHEMBL9256810 0.76 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19
SCHEMBL9862807 0.76 ALDH1A1 (0.34) ALDH1A1TSHRCYP2C19
SCHEMBL9267676 0.76 ALDH1A1 (0.34) ALDH1A1TSHRCYP2C19HTTAKT1
SCHEMBL3850181 0.76 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19
SCHEMBL8523523 0.76 ACHE (0.36) ALDH1A1
SCHEMBL1493083 0.76 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19
SCHEMBL9267683 0.76 CYP1A2 (0.35) ALDH1A1TSHRCYP2C19HTTAKT1
SCHEMBL8992328 0.76 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19
SCHEMBL7789586 0.76 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110526832-A A method of preparing polysubstituted alicyclic compound UNIV ZHEJIANG NORMAL 2019-12-03 CN claimed
CN-105073752-B Method for producing tricyclic compound and tricyclic compound producible by the production method 大鹏药品工业株式会社 2017-08-15 CN claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
EP-1259556-B1 IMPROVED DERIVATIVES OF SILANE FUNCTIONALIZED OLEFIN INTERPOLYMERS DOW GLOBAL TECHNOLOGIES INC (US) 2006-06-07 EP claimed
EP-1534664-A1 N-BISARYL- AND N-ARYL-CYCLOALKYLIDENYL-ALPHA-HYDROXY-AND ALPHA-ALKOXY ACID AMIDES Syngenta Participations AG (CH) 2005-06-01 EP claimed
WO-2004011417-A1 N-BISARYL- AND N-ARYL-CYCLOALKYLIDENYL-ALPHA-HYDROXY-AND ALPHA-ALKOXY ACID AMIDES SYNGENTA PARTICIPATIONS AG (CH) 2004-02-05 WO claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed
US-12384861-B2 Crosslinked compositions from olefin/silane interpolymers DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-12 US disclosed
EP-4597212-A1 CURABLE RESIN COMPOSITION FOR USE IN SEALING MATERIAL FOR FILM LIQUID CRYSTAL PANEL, AND FILM LIQUID CRYSTAL PANEL HAVING END SEALED BY SAID CURABLE RESIN COMPOSITION NOF Corporation (JP) 2025-08-06 EP disclosed
CN-120192630-A Resin composition 味之素株式会社 2025-06-24 CN disclosed
CN-120059458-A Resin composition 味之素株式会社 2025-05-30 CN disclosed
CN-116171304-B Cross-linking compositions from olefin/silane interpolymers 陶氏环球技术有限责任公司 2025-05-23 CN disclosed
CN-120021354-A Method for manufacturing circuit board 味之素株式会社 2025-05-20 CN disclosed
EP-0428365-A1 Aminomacrolides and derivatives having immunosuppressive activity MERCK & CO. INC. (US) 1991-05-22 EP disclosed
EP-0423714-A2 Hair revitalizing agent FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-04-24 EP disclosed
EP-0416609-A2 Benzo[b]thiophene-containing lipoxygenase-inhibiting compounds ABBOTT LABORATORIES (US) 1991-03-13 EP disclosed
US-4956352-A TREATING AUTOIMMUNE DISEASES, RESISTANCE TO TRANSPLANTATION, INFECTIONS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-09-11 US disclosed
US-4929611-A ANTIBODY INHIBITORS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-05-29 US disclosed
US-4894366-A Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-01-16 US disclosed