SCHEMBL7198219

SCHEMBL7198219

C=C[SiH](CCC)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8992356 0.90 PTGS2 (0.36) TSHR
SCHEMBL27841202 0.83 ALDH1A1 (0.33) ALDH1A1TSHRTP53
SCHEMBL27895965 0.79 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL10384708 0.75 CYP3A4 (0.30)
SCHEMBL14958525 0.75 RELA (0.31)
SCHEMBL29027172 0.74
SCHEMBL1493083 0.74 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL444984 0.74 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL21527924 0.74 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL10498995 0.73 ALDH1A1 (0.30) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6534595-B2 Blend of thermosetting resin, decomposable resin and solvent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-18 US disclosed
US-20010038887-A1 Coating solution for forming porous organic film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-08 US disclosed
US-5171792-A Crosslinkable saturated and unsaturated carbosilane polymers and formulations UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1992-12-15 US disclosed
US-5130390-A Crosslinkable saturated and unsaturated carbosilane polymers and formulations UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1992-07-14 US disclosed