Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398838 | 0.87 | GAA (0.59) | ALDH1A1FFAR1ALOX5OR51E2FFAR4 | |
| SCHEMBL5613276 | 0.87 | ALDH1A1 (0.59) | ALDH1A1ALOX5OR51E2METTSHR | |
| SCHEMBL7283109 | 0.86 | ALDH1A1 (0.57) | ALDH1A1ALOX5OR51E2METTSHR | |
| SCHEMBL347209 | 0.85 | FFAR4 (0.61) | ALDH1A1FFAR1ALOX5OR51E2FFAR4 | |
| Hydrochloric Acid SCHEMBL3225386 | 0.83 | FFAR4 (0.59) | ALDH1A1FFAR1ALOX5OR51E2FFAR4 | |
| SCHEMBL2729248 | 0.83 | GAA (0.68) | ALDH1A1TSHRGAANFKB1TDP1 | |
| SCHEMBL9516946 | 0.82 | ALDH1A1 (0.77) | ALDH1A1TSHRGAATDP1CYP19A1 | |
| SCHEMBL17537957 | 0.82 | POLB (0.54) | ALDH1A1FFAR1ALOX5OR51E2FFAR4 | |
| SCHEMBL3677143 | 0.82 | FFAR1 (0.56) | ALDH1A1FFAR1ALOX5OR51E2FFAR4 | |
| Dihydroferulic Acid SCHEMBL30210940 | 0.82 | ALOX5 (0.74) | ALDH1A1ALOX5OR51E2TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021065307-A1 | ANGIOTENSIN-CONVERTING ENZYME INHIBITOR, BLOOD PRESSURE-LOWERING AGENT, AND BEVERAGES AND FOOD PRODUCTS | 丸善製薬株式会社 | 2021-04-08 | — | — | WO | disclosed |
| CN-107973791-B | Fused or tricyclic aryl pyrimidine compounds as kinase inhibitors | 南京圣和药业股份有限公司 | 2020-04-07 | — | — | CN | disclosed |
| CN-107614503-B | Fused or tricyclic aryl pyrimidine compounds as kinase inhibitors | 广东众生药业股份有限公司 | 2020-03-10 | — | — | CN | disclosed |
| EP-2310371-B1 | PPAR AGONIST COMPOUNDS AND PREPARATION AND USES THEREOF FOR TREATING DIABETES AND/OR DYSLIPIDEMIA | GENFIT (FR) | 2013-05-15 | — | — | EP | disclosed |