Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 2/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | HSD11B1 | P28845 | 2/20 | 1.00 |
| ▸ | STAT3 | P40763 | 2/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 2/20 | 1.00 |
| ▸ | RELA | Q04206 | 2/20 | 1.00 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 1.00 |
| ▸ | APP | P05067 | 3/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.79 |
| ▸ | CA12 | O43570 | 2/20 | 0.79 |
| ▸ | CA1 | P00915 | 2/20 | 0.79 |
| ▸ | CA2 | P00918 | 2/20 | 0.79 |
| ▸ | CA3 | P07451 | 2/20 | 0.79 |
| ▸ | PKM | P14618 | 2/20 | 0.79 |
| ▸ | CA4 | P22748 | 2/20 | 0.79 |
| ▸ | CA6 | P23280 | 2/20 | 0.79 |
| ▸ | CA5A | P35218 | 2/20 | 0.79 |
| ▸ | SNCA | P37840 | 2/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1493283 | 1.00 | CYP2D6 (1.00) | CYP2D6CYP1A2ALOX5NFKB1HSD11B1 | |
| SCHEMBL30668505 | 1.00 | CYP2D6 (1.00) | CYP2D6CYP1A2ALOX5NFKB1HSD11B1 | |
| SCHEMBL29478095 | 1.00 | CYP2D6 (1.00) | CYP2D6CYP1A2ALOX5NFKB1HSD11B1 | |
| SCHEMBL19824721 | 0.95 | CYP2D6 (0.91) | CYP2D6CYP1A2ALOX5NFKB1HSD11B1 | |
| SCHEMBL2744233 | 0.95 | CYP2D6 (0.91) | CYP2D6CYP1A2ALOX5NFKB1HSD11B1 | |
| SCHEMBL2744234 | 0.95 | CYP2D6 (0.91) | CYP2D6CYP1A2ALOX5NFKB1HSD11B1 | |
| SCHEMBL15147249 | 0.94 | CYP2D6 (0.88) | CYP2D6CYP1A2ALOX5NFKB1HSD11B1 | |
| SCHEMBL15288997 | 0.94 | CYP2D6 (0.88) | CYP2D6CYP1A2ALOX5NFKB1HSD11B1 | |
| SCHEMBL17019805 | 0.94 | CYP2D6 (0.88) | CYP2D6CYP1A2ALOX5NFKB1HSD11B1 | |
| SCHEMBL5598747 | 0.92 | CYP2D6 (0.85) | CYP2D6CYP1A2ALOX5NFKB1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054365-B1 | METHODS TO PREPARE PENTA-1,4-DIEN-3-ONES AND SUBSTITUTED CYCLOHEXANONES AND DERIVATIVES WITH ANTITUMORAL AND ANTIPARASITIC PROPERTIES, THE COMPOUNDS AND THEIR USES | UNIBAN UNIVERSIDADE BANDEIRANTE DE S O PAULO (BR) | 2014-09-24 | — | — | EP | claimed |
| EP-1572614-B1 | METHOD FOR THE PREPARATION OF 1,5-BIS(4-HYDROXY-3-METOXY-PHENYL)-PENTA-1,4-DIEN-3-ONE | FUNDACAO DE AMPARO A PESQUISA DO ESTADO DE SAO PAULO (BR) | 2013-12-25 | — | — | EP | claimed |
| US-20100048957-A1 | METHOD TO PREPARE PURE CURCUMIN | KIM DARRICK S H L | 2010-02-25 | — | — | US | claimed |
| US-20100029763-A1 | METHODS TO PREPARE PENTA-1,4-DIEN-3-ONES AND SUBSTITUTED CYCLOHEXANONES AND DERIVATIVES WITH ANTITUMORAL AND ANTIPARASITIC PROPERTIES, THE COMPOUNDS AND THEIR USES | UNIVERSIDADE BANDEIRANTE DE SAO PAULO-ACADEMIA, PAULISTA ANCHIETA S/C LTDA (BR) | 2010-02-04 | — | — | US | claimed |
| US-7432401-B2 | Method for the preparation of 1,5-bis(4-hydroxy-3-metoxy-phenyl)-penta-1,4-dien-3-one and derivatives with antitumoral properties | Fundação de Amparo a Pesquisa Do Estado de São Paulo (BR) | 2008-10-07 | — | — | US | claimed |
| US-20060128997-A1 | New method for the preparation of 1,5-bis(4-hydroxy-3-metoxy-phenyl)-penta-1,4-dien-3-one and derivatives with antitumoral properties | FUNDACAO DE AMPARO A PESQUISA DO ESTADO DE SAO PAULO (BR) | 2006-06-15 | — | — | US | claimed |
| EP-1572614-A2 | NEW METHOD FOR THE PREPARATION OF 1,5-BIS(4-HYDROXY-3-METOXY-PHENYL)-PENTA-1,4-DIEN-3-ONE AND DERIVATIVES WITH ANTITUMORAL PROPERTIES | Fundacio de Amparo Pesquisa do Estado des Sao Paulo (BR) | 2005-09-14 | — | — | EP | claimed |
| WO-2004047716-A2 | NEW METHOD FOR THE PREPARATION OF 1,5-BIS(4-HYDROXY-3-METOXY-PHENYL)-PENTA-1,4-DIEN-3-ONE AND DERIVATIVES WITH ANTITUMORAL PROPERTIES | Fundação De Amparo À Pesquisa Do Estado de São Paulo (BR) | 2004-06-10 | — | — | WO | claimed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| US-20240158430-A1 | NOVEL COMPOUND OR SALT THEREOF, AND ANTITUMOR ACTIVATOR CONTAINING SAME AS ACTIVE INGREDIENT | AKITA UNIVERSITY (JP) | 2024-05-16 | — | — | US | disclosed |
| WO-2022190915-A1 | NOVEL COMPOUND OR SALT THEREOF, AND ANTITUMOR ACTIVATOR CONTAINING SAME AS ACTIVE INGREDIENT | 国立大学法人秋田大学 | 2022-09-15 | — | — | WO | disclosed |
| US-20220152001-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2022-05-19 | — | — | US | disclosed |
| US-11319273-B2 | Lipophilic curcumin analogs and methods of inhibiting HIV-1, treating latent HIV in the brain, and preventing HIV-mediated cognitive decline and HIV dementia | HOWARD UNIVERSITY (US) | 2022-05-03 | — | — | US | disclosed |
| WO-2004047716-A3 | NEW METHOD FOR THE PREPARATION OF 1,5-BIS(4-HYDROXY-3-METOXY-PHENYL)-PENTA-1,4-DIEN-3-ONE AND DERIVATIVES WITH ANTITUMORAL PROPERTIES | FUNDACAO DE AMPARO A PESQUISA (BR) | 2004-08-19 | — | — | WO | disclosed |
| WO-2004047716-A2 | NEW METHOD FOR THE PREPARATION OF 1,5-BIS(4-HYDROXY-3-METOXY-PHENYL)-PENTA-1,4-DIEN-3-ONE AND DERIVATIVES WITH ANTITUMORAL PROPERTIES | Fundação De Amparo À Pesquisa Do Estado de São Paulo (BR) | 2004-06-10 | — | — | WO | disclosed |
| WO-2004047716-A2 | NEW METHOD FOR THE PREPARATION OF 1,5-BIS(4-HYDROXY-3-METOXY-PHENYL)-PENTA-1,4-DIEN-3-ONE AND DERIVATIVES WITH ANTITUMORAL PROPERTIES | Fundação De Amparo À Pesquisa Do Estado de São Paulo (BR) | 2004-06-10 | — | — | WO | disclosed |
| JP-2001048756-A | HAIR GROWER | KANEBO LTD | 2001-02-20 | — | — | JP | disclosed |
| US-6043334-A | USEFUL FOR PRODUCTION OF CROSSLINKED POLYCARBONATE RESINS; ELECTROPHOTOGRAPHIC PHOTORECEPTORS, WHICH HAVE PHOTOSENSITIVE LAYER CONTAINING CROSSLINKED POLYCARBONATE RESINS | IDEMITSU KOSAN CO., LTD. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0866083-A1 | POLYCARBONATE RESIN, CROSSLINKED POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1998-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158430-A1 | NOVEL COMPOUND OR SALT THEREOF, AND ANTITUMOR ACTIVATOR CONTAINING SAME AS ACTIVE INGREDIENT | STAT3, STAT6, HDAC1 | CYP2D6 4844/4885CYP1A2 4831/4885ALOX5 566/4885 |
| US-20060128997-A1 | New method for the preparation of 1,5-bis(4-hydroxy-3-metoxy-phenyl)-penta-1,4-dien-3-one and derivatives with antitumoral properties | DDB1, ANXA1, ANXA5 | CYP2D6 1648/4885CYP1A2 2477/4885ALOX5 819/4885 |
| US-11319273-B2 | Lipophilic curcumin analogs and methods of inhibiting HIV-1, treating latent HIV in the brain, and preventing HIV-mediated cognitive decline and HIV dementia | BACE1, GAA, GLA | CYP2D6 1912/4885CYP1A2 1886/4885ALOX5 1209/4885 |
| US-20220152001-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | CYP2D6 2367/4885CYP1A2 2166/4885ALOX5 1897/4885 |
| US-20100029763-A1 | METHODS TO PREPARE PENTA-1,4-DIEN-3-ONES AND SUBSTITUTED CYCLOHEXANONES AND DERIVATIVES WITH ANTITUMORAL AND ANTIPARASITIC PROPERTIES, THE COMPOUNDS AND THEIR USES | CASP3, CYP8B1, DERA | CYP2D6 26/4885CYP1A2 71/4885ALOX5 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.