SCHEMBL14933496

SCHEMBL14933496

O=c1c2c3ccccc3ccc2c2ccccc2n1-c1ccc2ccccc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
RAB9A P51151 2/20 0.44
POLB P06746 2/20 0.44
PMM2 O15305 1/20 0.44
MPI P34949 1/20 0.44
PHOSPHO1 Q8TCT1 1/20 0.44
NPC1 O15118 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
GAA P10253 1/20 0.43
HPGD P15428 2/20 0.42
HSP90AA1 P07900 1/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
TSHR P16473 1/20 0.39
BRCA1 P38398 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14933494 0.86 KDM4E (0.53) ALDH1A1POLBPMM2MPIPHOSPHO1
SCHEMBL14933498 0.84 ALDH1A1 (0.50) ALDH1A1RAB9APOLBPMM2MPI
SCHEMBL22198418 0.82 HPGD (0.45) ALDH1A1RAB9APOLBPMM2MPI
SCHEMBL25828268 0.81 KDM4E (0.41) ALDH1A1RAB9APOLBPMM2MPI
SCHEMBL30320243 0.81 KDM4E (0.56) ALDH1A1RAB9APOLBPMM2MPI
SCHEMBL274318 0.81 KDM4E (0.56) ALDH1A1RAB9APOLBPMM2MPI
SCHEMBL18019954 0.80 CYP1A2 (0.50) ALDH1A1RAB9APOLBPMM2MPI
SCHEMBL17071103 0.79 ALDH1A1 (0.35) ALDH1A1RAB9APOLBPMM2MPI
SCHEMBL16409623 0.79 KDM4E (0.50) ALDH1A1RAB9APOLBPMM2MPI
SCHEMBL16409588 0.79 KDM4E (0.50) ALDH1A1RAB9APOLBPMM2MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
EP-2773721-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-25 EP disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
WO-2013064206-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-05-10 WO disclosed