Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 12/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | TLR9 | Q9NR96 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.63 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | CASP6 | P55212 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14933689 | 0.91 | TNF (0.83) | TNFMEN1KMT2ANPC1TLR9 | |
| SCHEMBL14933668 | 0.80 | TNF (0.66) | TNFMEN1KMT2ANPC1MAPT | |
| SCHEMBL13401768 | 0.74 | MEN1 (1.00) | TNFMEN1KMT2ANPC1TLR9 | |
| SCHEMBL5708771 | 0.71 | NPC1 (0.73) | TNFMEN1KMT2ANPC1TLR9 | |
| SCHEMBL13401763 | 0.70 | MAPT (0.65) | TNFMEN1KMT2ANPC1TLR9 | |
| SCHEMBL3707610 | 0.70 | MEN1 (0.61) | TNFMEN1KMT2ANPC1TLR9 | |
| SCHEMBL4588213 | 0.69 | L3MBTL1 (0.55) | TNFMEN1KMT2ANPC1MAPT | |
| SCHEMBL5708833 | 0.68 | NPC1 (1.00) | TNFMEN1KMT2ANPC1TLR9 | |
| SCHEMBL3502541 | 0.68 | MEN1 (0.50) | TNFMEN1KMT2ANPC1TLR9 | |
| SCHEMBL15717208 | 0.68 | EPAS1 (0.69) | TNFMEN1KMT2ANPC1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140296308-A1 | DRUGS FOR INHIBITING P38 AND USES THEREOF | Universidad Autónoma de Madrid (ES) | 2014-10-02 | — | — | US | claimed |
| EP-2774613-A1 | DRUGS FOR INHIBITING P38 AND USES THEREOF | Universidad Autónoma De Madrid (ES) | 2014-09-10 | — | — | EP | claimed |
| US-9096554-B2 | Drugs for inhibiting p38 and uses thereof | Universidad Autónoma de Madrid (ES) | 2015-08-04 | — | — | US | disclosed |
| US-9096554-B2 | Drugs for inhibiting p38 and uses thereof | Universidad Autónoma de Madrid (ES) | 2015-08-04 | — | — | US | disclosed |
| US-20140296308-A1 | DRUGS FOR INHIBITING P38 AND USES THEREOF | Universidad Autónoma de Madrid (ES) | 2014-10-02 | — | — | US | disclosed |
| US-20140296308-A1 | DRUGS FOR INHIBITING P38 AND USES THEREOF | Universidad Autónoma de Madrid (ES) | 2014-10-02 | — | — | US | disclosed |
| EP-2774613-A1 | DRUGS FOR INHIBITING P38 AND USES THEREOF | Universidad Autónoma De Madrid (ES) | 2014-09-10 | — | — | EP | disclosed |
| EP-2774613-A1 | DRUGS FOR INHIBITING P38 AND USES THEREOF | Universidad Autónoma De Madrid (ES) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064714-A1 | DRUGS FOR INHIBITING P38 AND USES THEREOF | Universidad Autónoma de Madrid (ES) | 2013-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296308-A1 | DRUGS FOR INHIBITING P38 AND USES THEREOF | MAPK1, MAPK4, MAPK8 | TNF 107/4885MEN1 3940/4885KMT2A 3069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.