Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.73 |
| ▸ | TLR9 | Q9NR96 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | RAB9A | P51151 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | HTT | P42858 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | XBP1 | P17861 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 10/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.67 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.67 |
| ▸ | LIG1 | P18858 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708833 | 0.84 | NPC1 (1.00) | NPC1TLR9MAPTRAB9AALDH1A1 | |
| SCHEMBL300103 | 0.77 | GAA (0.59) | NPC1TLR9MAPTRAB9AALDH1A1 | |
| SCHEMBL5708737 | 0.76 | MEN1 (0.64) | NPC1TLR9MAPTRAB9AALDH1A1 | |
| SCHEMBL7089706 | 0.75 | MEN1 (0.66) | NPC1TLR9MAPTRAB9AALDH1A1 | |
| SCHEMBL13401763 | 0.75 | MAPT (0.65) | NPC1TLR9MAPTRAB9AALDH1A1 | |
| SCHEMBL5708797 | 0.74 | ALDH1A1 (0.48) | NPC1TLR9MAPTRAB9AALDH1A1 | |
| SCHEMBL5708810 | 0.74 | ALDH1A1 (0.48) | NPC1TLR9MAPTRAB9AALDH1A1 | |
| SCHEMBL5708820 | 0.74 | MAPT (0.54) | NPC1TLR9MAPTRAB9AALDH1A1 | |
| SCHEMBL13401485 | 0.74 | LIG1 (1.00) | NPC1TLR9MAPTRAB9AALDH1A1 | |
| SCHEMBL3707610 | 0.72 | MEN1 (0.61) | NPC1TLR9MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328244-B1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AG (DE) | 2006-10-11 | — | — | EP | claimed |
| US-6773463-B2 | A MIXTURE OF A 4-NITRO-2,1,3-BENZOXADIAZOLE, A 4-NITRO-2,1,3-BENZOTHIADIAZOLE, OR A 4-NITRO-2,1,3-BENZO-SELENADIAZOLE AND AT LEAST ONE AMINE, PHENOL, OR AMINONITROBENZENE; INTENSE COLORATIONS; MILD CONDITIONS; DIRECT HAIR DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | claimed |
| EP-1328244-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2003-07-23 | — | — | EP | claimed |
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-04-17 | — | — | US | claimed |
| WO-2002022093-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | claimed |
| US-20080311150-A1 | Novel sequences encoding hepatitis C virus glycoproteins | DUMONCEAUX JULIE | 2008-12-18 | — | — | US | disclosed |
| US-20080311150-A1 | Novel sequences encoding hepatitis C virus glycoproteins | DUMONCEAUX JULIE | 2008-12-18 | — | — | US | disclosed |
| US-7361503-B2 | Sequences encoding hepatitis C virus glycoproteins | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2008-04-22 | — | — | US | disclosed |
| EP-1328244-B1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AG (DE) | 2006-10-11 | — | — | EP | disclosed |
| EP-0884390-B1 | Method for producing an optically active compound | KYOWA HAKKO KOGYO KK (JP) | 2006-05-10 | — | — | EP | disclosed |
| US-6773463-B2 | A MIXTURE OF A 4-NITRO-2,1,3-BENZOXADIAZOLE, A 4-NITRO-2,1,3-BENZOTHIADIAZOLE, OR A 4-NITRO-2,1,3-BENZO-SELENADIAZOLE AND AT LEAST ONE AMINE, PHENOL, OR AMINONITROBENZENE; INTENSE COLORATIONS; MILD CONDITIONS; DIRECT HAIR DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | disclosed |
| EP-1328244-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002022093-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | disclosed |
| US-20020006645-A1 | Method for producing optically active compound | HASHIMOTO SHIN-ICHI (JP) | 2002-01-17 | — | — | US | disclosed |
| EP-0641862-B1 | Process for producing trans-4-hydroxy-L-proline | KYOWA HAKKO KOGYO KK (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-6207427-B1 | ALLOWING RECOMBINANT MICROORGANISM CARRYING RECOMBINANT DNA HARBORING (S)-4-HYDROXY-2-KETOGLUTARIC ACID ALDOLASE GENE TO ACT ON SUGAR AND GLYOXYLIC ACID IN AN AQUEOUS MEDIUM, AND COLLECTING OPTICALLY ACTIVE (S)-4-HYDROXY-2-KETOGLUTARIC ACID | KYOWA HAKKO KOGYO, LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0884390-A2 | Method for producing an optically active compound | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-12-16 | — | — | EP | disclosed |
| EP-0645457-B1 | L-proline-3-hydroxylase and process for producing cis-3-hydroxy-L-proline | KYOWA HAKKO KOGYO KK (JP) | 1998-04-01 | — | — | EP | disclosed |
| EP-0645457-A2 | Process for producing cis-3-hydroxy-L-proline | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |
| US-5248770-A | Labels such as fluorescent or radioactive compounds | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | KRT18, AOC1, S100B | NPC1 4185/4885TLR9 4225/4885MAPT 2273/4885 |
| US-20080311150-A1 | Novel sequences encoding hepatitis C virus glycoproteins | HAVCR2, EEA1, SELPLG | NPC1 325/4885TLR9 2286/4885MAPT 4832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.