Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5276860 | 0.91 | ALDH1A1 (0.50) | KMT2AGAAMEN1ALDH1A1LMNA | |
| SCHEMBL5276866 | 0.91 | ALDH1A1 (0.50) | KMT2AGAAMEN1ALDH1A1LMNA | |
| SCHEMBL14919146 | 0.86 | MAPT (0.51) | MAPK1MAPTKMT2AGAATDP1 | |
| SCHEMBL14919145 | 0.86 | MAPT (0.51) | MAPK1MAPTKMT2AGAATDP1 | |
| SCHEMBL23211250 | 0.82 | ALDH1A1 (0.49) | MAPTELANEKMT2AGAAMEN1 | |
| SCHEMBL9375780 | 0.82 | ALDH1A1 (0.54) | MAPK1MAPTKMT2AGAAMEN1 | |
| SCHEMBL9375784 | 0.82 | ALDH1A1 (0.54) | MAPK1MAPTKMT2AGAAMEN1 | |
| SCHEMBL14454666 | 0.82 | ALDH1A1 (0.54) | MAPTKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL28501453 | 0.82 | ELANE (0.48) | ELANEKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL28501455 | 0.82 | ELANE (0.48) | ELANEKMT2AGAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066838-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |