SCHEMBL14934067

SCHEMBL14934067

O=c1[nH]c2cc(F)c(C(F)(C(F)(F)F)C(F)(F)F)cc2[nH]1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 4/20 0.38
PDE3A Q14432 4/20 0.38
GRIA1 P42261 2/20 0.34
GRIA2 P42262 1/20 0.34
GRIA3 P42263 1/20 0.34
GRIA4 P48058 1/20 0.34
MAPT P10636 4/20 0.33
GAA P10253 2/20 0.33
ALDH1A1 P00352 4/20 0.32
KLK7 P49862 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PKM P14618 1/20 0.32
DAO P14920 1/20 0.32
KDM4E B2RXH2 2/20 0.31
KMT2A Q03164 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3786399 0.78 PDE3B (0.50) PDE3BPDE3AGRIA1MAPTGAA
SCHEMBL463637 0.73 GRIA1 (0.54) GRIA1GRIA2GRIA3GRIA4MAPT
SCHEMBL31748445 0.68 MAPT (0.42) PDE3BPDE3AMAPTGAAALDH1A1
SCHEMBL17758383 0.68 PDE3B (0.41) PDE3BPDE3AGRIA1MAPTGAA
SCHEMBL15322773 0.68 GRIN2D (0.50) PDE3BPDE3AGRIA1GRIA2GRIA3
SCHEMBL1439986 0.68 ALDH1A1 (0.63) PDE3BPDE3AGRIA1GRIA2GRIA3
SCHEMBL22725084 0.68 MAPT (0.42) PDE3BPDE3AMAPTGAAALDH1A1
SCHEMBL2416635 0.68 GRIA1 (0.45) PDE3BPDE3AGRIA1GRIA2GRIA3
SCHEMBL16221712 0.65 TYRO3 (0.37) PDE3BPDE3AGRIA1GAAPKM
SCHEMBL15932949 0.64 GRIN2D (0.55) PDE3BPDE3AGRIA1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013065725-A1 PHTHALAMIDE DERIVATIVE, PESTICIDE FOR AGRICULTURAL AND HORTICULTURAL APPLICATIONS WHICH COMPRISES SAID DERIVATIVE, AND METHOD OF UTILIZING SAID PESTICIDE 日本農薬株式会社 (JP) 2013-05-10 WO disclosed