Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338752 | 0.80 | CHEK2 (0.49) | GAAFYNMAP4K4AURKATTK | |
| Hydrochloric Acid SCHEMBL11244234 | 0.77 | CHEK2 (0.47) | FYNMAP4K4AURKATTKAURKB | |
| SCHEMBL28107568 | 0.76 | CYP2A6 (0.56) | FYNMAP4K4CYP1A2CHEK2JAK2 | |
| SCHEMBL14934133 | 0.75 | USP7 (0.46) | CYP11B2USP7MAP4K4DHFRCYP1A2 | |
| SCHEMBL3946383 | 0.74 | GAA (0.52) | GAACYP11B2LIMK1AURKAAURKB | |
| SCHEMBL29157896 | 0.73 | GAA (0.48) | GAARPS6KA3CYP17A1CYP1A2 | |
| SCHEMBL14934135 | 0.72 | CYP11B2 (0.57) | CYP11B2USP7MAP4K4ALOX5APFEN1 | |
| SCHEMBL2942923 | 0.72 | CDC25B (0.50) | GAALIMK1RPS6KA3CYP17A1 | |
| SCHEMBL30350188 | 0.72 | CDC25B (0.50) | GAALIMK1RPS6KA3CYP17A1 | |
| SCHEMBL17067708 | 0.71 | USP7 (0.39) | USP7FYNMAP4K4DHFRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773631-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | EP | disclosed |
| WO-2013064519-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-05-10 | — | — | WO | disclosed |