Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1975118 | 0.91 | HSD17B10 (0.38) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL3871975 | 0.74 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL11811716 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL1976151 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL3871969 | 0.72 | TSHR (0.38) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL3872578 | 0.72 | TSHR (0.38) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL3870859 | 0.72 | TSHR (0.38) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL23827482 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL12963490 | 0.71 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL10273104 | 0.66 | ALDH1A1 (0.31) | ALDH1A1MEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447082-B2 | Optically active fluconazole analogues containing thiophenes as antifungal agents | FDC LIMITED (IN) | 2016-09-20 | — | — | US | disclosed |
| US-20140249194-A1 | OPTICALLY ACTIVE FLUCONAZOLE ANALOGUES CONTAINING THIOPHENES AS ANTIFUNGAL AGENTS | FDC LIMITED (IN) | 2014-09-04 | — | — | US | disclosed |
| WO-2013065065-A1 | OPTICALLY ACTIVE FLUCONAZOLE ANALOGUES CONTAINING THIOPHENES AS ANTIFUNGAL AGENTS | FDC LIMITED (IN) | 2013-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249194-A1 | OPTICALLY ACTIVE FLUCONAZOLE ANALOGUES CONTAINING THIOPHENES AS ANTIFUNGAL AGENTS | CYP3A4, CYP4B1, CBR1 | ALDH1A1 1476/4885MEN1 1090/4885KMT2A 2444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.