Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11811716 | 0.93 | ALDH1A1 (0.44) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL1974446 | 0.86 | ALDH1A1 (0.38) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL3870859 | 0.82 | TSHR (0.38) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL3871969 | 0.82 | TSHR (0.38) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL3872578 | 0.82 | TSHR (0.38) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL28846698 | 0.75 | — | — | |
| SCHEMBL3871975 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL15274376 | 0.75 | ALOX15 (0.47) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| SCHEMBL3345196 | 0.71 | MAOB (0.43) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL14934236 | 0.71 | ALDH1A1 (0.36) | ALDH1A1TSHRHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864312-B1 | NOVEL ANTI-CANCER THIOPHENE COMPOUNDS | UNIV LEUVEN KATH (BE) | 2021-09-22 | — | — | EP | claimed |