Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16838135 | 0.79 | KDM4E (0.33) | ALDH1A1 | |
| SCHEMBL25370588 | 0.76 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL1975118 | 0.75 | HSD17B10 (0.38) | ALDH1A1 | |
| SCHEMBL24553664 | 0.74 | PGK1 (0.39) | ALDH1A1 | |
| SCHEMBL12830087 | 0.73 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL14934236 | 0.73 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL11637103 | 0.73 | VCAM1 (0.37) | ALDH1A1 | |
| SCHEMBL24834186 | 0.71 | — | — | |
| SCHEMBL16863726 | 0.70 | — | — | |
| SCHEMBL8100154 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447082-B2 | Optically active fluconazole analogues containing thiophenes as antifungal agents | FDC LIMITED (IN) | 2016-09-20 | — | — | US | disclosed |
| US-20140249194-A1 | OPTICALLY ACTIVE FLUCONAZOLE ANALOGUES CONTAINING THIOPHENES AS ANTIFUNGAL AGENTS | FDC LIMITED (IN) | 2014-09-04 | — | — | US | disclosed |
| WO-2013065065-A1 | OPTICALLY ACTIVE FLUCONAZOLE ANALOGUES CONTAINING THIOPHENES AS ANTIFUNGAL AGENTS | FDC LIMITED (IN) | 2013-05-10 | — | — | WO | disclosed |
| EP-2346861-B1 | THIOPHENE CONTAINING ANALOGUES OF FLUCONAZOLE AS ANTIFUNGAL AGENTS AND PROCESS THEREOF | COUNCIL SCIENT IND RES (IN) | 2013-01-23 | — | — | EP | disclosed |
| US-8236840-B2 | Thiopene containing analogues of fluconazole as antifungal agents and process for their preparation | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-08-07 | — | — | US | disclosed |
| EP-2346861-A2 | THIOPHENE CONTAINING ANALOGUES OF FLUCONAZOLE AS ANTIFUNGAL AGENTS AND PROCESS THEREOF | Council of Scientific and Industrial Research (IN) | 2011-07-27 | — | — | EP | disclosed |
| US-20110144171-A1 | THIOPENE CONTAINING ANALOGUES OF FLUCONAZOLE AS ANTIFUNGAL AGENTS AND PROCESS FOR THEIR PREPARATION | COUNCIL OF SCIENCE & INDUSTRIAL RESEARCH (IN) | 2011-06-16 | — | — | US | disclosed |
| WO-2010046912-A2 | THIOPHENE CONTAINING ANALOGUES OF FLUCONAZOLE AS ANTIFUNGAL AGENTS AND PROCESS THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249194-A1 | OPTICALLY ACTIVE FLUCONAZOLE ANALOGUES CONTAINING THIOPHENES AS ANTIFUNGAL AGENTS | CYP3A4, CYP4B1, CBR1 | ALDH1A1 1476/4885 |
| US-20110144171-A1 | THIOPENE CONTAINING ANALOGUES OF FLUCONAZOLE AS ANTIFUNGAL AGENTS AND PROCESS FOR THEIR PREPARATION | CYP51A1, ERG28, TPMT | ALDH1A1 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.