SCHEMBL1493437

SCHEMBL1493437

NC1=Cc2ccccc2ON1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
NISCH Q9Y2I1 1/20 0.31
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
UBE2N P61088 1/20 0.31
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29139526 0.90 NISCH (0.30) MEN1MAPTKMT2AKDM4EALDH1A1
(Phenylsulfonyl)Benzene SCHEMBL29028248 0.84 HTR6 (0.45) TSHR
SCHEMBL3074957 0.76 ALOX5 (0.37) MEN1MAPTKMT2ANISCHTP53
SCHEMBL5360794 0.75 ALDH1A1 (0.33) MEN1MAPTKMT2AKDM4EALDH1A1
SCHEMBL31346914 0.75 ALDH1A1 (0.33) MEN1MAPTKMT2AKDM4EALDH1A1
SCHEMBL29664451 0.74 NISCH (0.32) MEN1MAPTKMT2ANISCHTP53
SCHEMBL2075819 0.73 ALOX5 (0.35) MEN1MAPTKMT2AKDM4EALDH1A1
SCHEMBL1871103 0.73 MEN1 (0.34) MEN1MAPTKMT2ANISCHTP53
SCHEMBL1491185 0.73 ALOX5 (0.32) MEN1MAPTKMT2AKDM4EALDH1A1
SCHEMBL5181282 0.73 TSHR (0.34) MEN1MAPTKMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120082078-A Masking protection film for automobile paint spraying and preparation method thereof 青岛奥盛塑胶有限公司 2025-06-03 CN claimed
CN-119242286-A High-temperature-resistant foaming agent and preparation method thereof 滨州乾坤化工机械有限公司 2025-01-03 CN claimed
CN-118599406-A Anti-slip coating and preparation method thereof 廊坊赛尔孚环保科技有限公司 2024-09-06 CN claimed
CN-118272004-B Polyethylene adhesive and preparation method thereof 广饶齐成新能源有限公司 2024-07-26 CN claimed
CN-118272004-A Polyethylene adhesive and preparation method thereof 广饶齐成新能源有限公司 2024-07-02 CN claimed
CN-118109945-A High-strength flame-retardant elastic fabric and preparation method thereof 合肥楚欣纺织有限公司 2024-05-31 CN claimed
CN-118088793-A High-strength steel wire mesh composite polyethylene pipe and preparation method thereof 河南青龙塑料管业有限公司 2024-05-28 CN claimed
CN-112673043-B Curing agent composition for epoxy resin mixtures, epoxy resin mixtures and multicomponent epoxy resin systems 喜利得股份公司 2024-03-29 CN claimed
CN-113582939-B Secondary amino benzoxazine monomer and application thereof 北京理工大学 2023-03-21 CN claimed
US-11542391-B2 Hardener component for multi-component epoxy resin material, and multi-component epoxy resin material HILTI AKTIENGESELLSCHAFT (LI) 2023-01-03 US claimed
US-20020194685-A1 Composition for dyeing keratin fibres, comprising a pyrazoline-4, 5-dione and an aromatic primary amine L'OREAL S.A. (FR) 2002-12-26 US claimed
US-6464732-B2 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-10-15 US claimed
WO-2001016139-A9 ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARM INC (US) 2002-09-19 WO claimed
EP-1212330-A1 ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS INCORPORATED (US) 2002-06-12 EP claimed
US-20020040508-A1 COMPOSITION FOR DYEING KERATIN FIBRES,COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE L'OREAL S.A. (FR) 2002-04-11 US claimed
WO-2001016139-A1 ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS INCORPORATED (US) 2001-03-08 WO claimed
EP-0981320-A1 COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE L'OREAL (FR) 2000-03-01 EP claimed
WO-1998051268-A1 COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE L'OREAL (FR) 1998-11-19 WO claimed
CN-1051910-A Benzoxazine derivatives and pharmaceutical compositions containing them YAMANOUCHI PHARMRCEUTICAL (JP) 1991-06-05 CN claimed
EP-0103797-B1 SUBSTITUTED BENZOXAZINE DERIVATIVES BAYER AG (DE) 1986-11-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020194685-A1 Composition for dyeing keratin fibres, comprising a pyrazoline-4, 5-dione and an aromatic primary amine KRT18, KLK5, MARK1 MEN1 3401/4885MAPT 591/4885KMT2A 1376/4885
US-20020040508-A1 COMPOSITION FOR DYEING KERATIN FIBRES,COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE KRT18, KLK5, H1-5 MEN1 3896/4885MAPT 562/4885KMT2A 1176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.