Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14920895 | 1.00 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL16108268 | 1.00 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL16141290 | 1.00 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL16141289 | 1.00 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL14934470 | 1.00 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL3202585 | 0.87 | SLC6A2 (0.46) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL3202600 | 0.87 | SLC6A2 (0.46) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL3202592 | 0.87 | SLC6A2 (0.46) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL3194556 | 0.84 | SLC6A2 (0.66) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL3194570 | 0.84 | SLC6A2 (0.66) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9630929-B2 | Benzenesulfonamide compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2017-04-25 | — | — | US | disclosed |
| EP-2773637-B1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2016-06-08 | — | — | EP | disclosed |
| US-20140296245-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS, INC. (CA) | 2014-10-02 | — | — | US | disclosed |
| WO-2013064983-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2013-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296245-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | TRPV1, TRPA1, TRPV3 | SLC6A3 186/4885SLC6A4 168/4885SLC6A2 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.