Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14890602 | 0.73 | SYK (0.71) | SYK | |
| SCHEMBL23993917 | 0.72 | ALDH1A1 (0.47) | SYKLMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL3720418 | 0.70 | PDE1B (0.33) | L3MBTL1MAPTALDH1A1 | |
| SCHEMBL31528267 | 0.68 | LMNA (0.41) | LMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL14670938 | 0.68 | SYK (0.34) | SYKLMNAL3MBTL1ALDH1A1APOBEC3A | |
| SCHEMBL3010219 | 0.65 | CYP19A1 (0.39) | LMNAMAPTALDH1A1APOBEC3A | |
| SCHEMBL805514 | 0.64 | KDM4E (0.43) | L3MBTL1MAPT | |
| SCHEMBL23994211 | 0.63 | LMNA (0.37) | LMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL1202772 | 0.63 | L3MBTL1 (0.41) | L3MBTL1MAPT | |
| SCHEMBL12016060 | 0.62 | KDM4C (0.44) | LMNAL3MBTL1KDM4CKDM6BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013064445-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-05-10 | — | — | WO | disclosed |