Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.49 |
| ▸ | NOS1 | P29475 | 4/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | CLK1 | P49759 | 2/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | CLK3 | P49761 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29636278 | 0.77 | ROCK2 (0.53) | ROCK2NOS1ROCK1MAPTRAB9A | |
| SCHEMBL481818 | 0.77 | ROCK2 (0.53) | ROCK2NOS1ROCK1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL29957203 | 0.75 | ROCK2 (0.52) | ROCK2NOS1ROCK1MAPTRAB9A | |
| SCHEMBL1141784 | 0.73 | RAB9A (0.57) | ROCK2NOS1ROCK1MAPTRAB9A | |
| SCHEMBL14983547 | 0.71 | TUBB4A (0.47) | MAPTRAB9AMEN1GAAKMT2A | |
| SCHEMBL8835 | 0.70 | ROCK1 (0.41) | ROCK2NOS1ROCK1MAPTRAB9A | |
| SCHEMBL348190 | 0.70 | NPC1 (0.58) | ROCK2ROCK1RAB9AMEN1KMT2A | |
| SCHEMBL29643714 | 0.70 | NPC1 (0.58) | ROCK2ROCK1RAB9AMEN1KMT2A | |
| SCHEMBL29409358 | 0.70 | ROCK2 (0.59) | ROCK2NOS1ROCK1MAPTRAB9A | |
| SCHEMBL12872 | 0.70 | ROCK2 (0.59) | ROCK2NOS1ROCK1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110357813-A | A kind of new indole amine 2,3- dioxygenase inhibitor and its preparation method and application | 信达生物制药(苏州)有限公司 | 2019-10-22 | — | — | CN | disclosed |
| WO-2013064445-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-05-10 | — | — | WO | disclosed |